Results 91 to 100 of about 1,525,477 (300)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On the fundamental resonant mode of inhomogeneous soil deposits [PDF]

open access: yes, 2020
The problem of estimating seismic ground deformation is central to state-of-practice procedures of designing and maintaining infrastructure in earthquake-prone areas.
Asimaki, Domniki, Garcia-Suarez, Joaquin
core  

Frequency Response Characteristic (FRC) Curve and Fast Frequency Response Assessment in High Renewable Power Systems

open access: yes, 2020
This letter introduces a frequency response characteristic (FRC) curve and its application in high renewable power systems. In addition, the letter presents a method for fast frequency response assessment and frequency nadir prediction without performing dynamic simulations using detailed models.
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Experimental Validation of a Diesel Genset Frequency Dynamics Model for Use in Remote Area Power Systems

open access: yesIEEE Access
Diesel generators (gensets) are often the lowest-cost electric generation for reliable supply in remote microgrids. The development of converter-dominated diesel-backed microgrids requires accurate dynamic modeling to ensure power quality and system ...
Manisha Rauniyar   +9 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Techno-Economic Feasibility of Fuel Cell Vehicle-to-Grid Fast Frequency Control in Non-Interconnected Islands

open access: yesHydrogen
This paper presents an innovative approach to fast frequency control in electric grids by leveraging parked fuel cell electric vehicles (FCEVs), especially heavy-duty vehicles such as trucks.
Tziotas Christos   +2 more
doaj   +1 more source

Rapid adaptation of a polygenic trait after a sudden environmental shift

open access: yes, 2017
Although a number of studies have shown that natural and laboratory populations initially well-adapted to their environment can evolve rapidly when conditions suddenly change, the dynamics of rapid adaptation are not well understood.
Jain, Kavita, Stephan, Wolfgang
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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