Results 61 to 70 of about 2,898,059 (299)
Multi-Layer Visualization of Mobile Mapping Data [PDF]
application various different visualization schemes are conceivable. This paper presents a multi-layer based visualization method, enabling fast data browsing of mobile mapping data.
D. Eggert, M. Sester
doaj +1 more source
Fast generation of centroids for MAP-Elites
The use of MAP-Elites in high-dimensional behavioral spaces requires a scalable method for dividing the space into regions of equal volume. So far, the recommended approach to generate these regions has been the Centroidal Voronoi Tesselation (CVT), but this algorithm has a significant computational cost (typically a few minutes for more than 50 ...
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique ...
Alejandro Burga +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Fast 3D Semantic Mapping in Road Scenes
Fast 3D reconstruction with semantic information in road scenes is of great requirements for autonomous navigation. It involves issues of geometry and appearance in the field of computer vision.
Xuanpeng Li +4 more
doaj +1 more source
INDOOR MOBILE POSITIONING BASED ON LIDAR DATA AND CODED SEQUENCE PATTERN [PDF]
This paper proposed a coded sequence pattern for automatic matching of LiDAR point data, the methods including SIFT features, Otsu segmentation and Fast Hough transformation for the identification, positioning and interpret of the coded sequence patterns,
Z. Wang, B. Dong, D. Chen
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

