Results 61 to 70 of about 1,020,507 (332)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

High Efficiency Intra CU Partition and Mode Decision Method for VVC

IEEE Access, 2022
Versatile video coding (VVC/H.266) is the newest video compression standard, which is developed by the Joint Video Experts Team. Compared with previous encoding schemes, VVC achieves higher compression efficiency by introducing a new partition structure ...
Chi-Ting Ni, Shih-Hsiang Lin, Pei-Yin Chen, Yu-Ting Chu   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Synergistic combination of systems for structural health monitoring and earthquake early warning for structural health prognosis and diagnosis [PDF]

, 2012
Earthquake early warning (EEW) systems are currently operating nationwide in Japan and are in beta-testing in California. Such a system detects an earthquake initiation using online signals from a seismic sensor network and broadcasts a warning of the ...
Beck, James L., Wu, Stephen
core   +1 more source

Fast and adaptive mode decision and CU partition early termination algorithm for intra-prediction in HEVC

EURASIP Journal on Image and Video Processing, 2017
High Efficiency Video Coding (HEVC or H.265), the latest international video coding standard, displays a 50% bit rate reduction with nearly equal quality and dramatically higher coding complexity compared with H.264.
Mengmeng Zhang, Xiaojun Zhai, Zhi Liu
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An Electric Vehicle Charging Management Scheme Based on Publish/Subscribe Communication Framework

, 2016
Motivated by alleviating CO$_2$ pollution, Electric Vehicle (EV) based applications have recently received wide interests from both commercial and research communities by using electric energy instead of traditional fuel energy.
Cao, Yue, Kamel, George, Kim, Young-jin, Wang, Ning   +3 more
core   +1 more source

Fast CU Partition Decision Method Based on Texture Characteristics for H.266/VVC

IEEE Access, 2020
The versatile video coding (VVC) is the latest video coding standard, which uses a Multi-Type Tree (MTT) coding structure. Compared with existing video coding standards, this structure can flexibly split coding blocks according to the complex texture ...
Qiuwen Zhang, Yongbo Zhao, Bin Jiang, Lixun Huang, Tao Wei   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source