Results 71 to 80 of about 6,488,308 (244)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Efficient intra- and inter-mode selection algorithms for H.264/AVC [PDF]

, 2004
H.264/AVC standard is one of the most popular video formats for the next generation video coding. It provides a better performance in compression capability and visual quality compared to any existing video coding standards.
Yu, Andy C.
core  

Multi-class support vector machine-based fast algorithm for 3D-HEVC depth video intra coding

Tongxin xuebao, 2016
The recursive splitting process of largest coding unit (LCU) and the mode search process of coding unit imposed enormous computational complexity on encoder.
Sheng LIU, Zong-ju PENG, Jia-li CHEN, Fen CHEN, Mei YU, Gang-yi JIANG   +5 more
doaj   +2 more sources

Intra-Skip in Inter-Frame Coding of H.264/AVC

International Journal of Digital Multimedia Broadcasting, 2009
In inter-frame coding of H.264/AVC standard, not only seven inter-partition modes but also intra-modes are taken into account for seeking the best coding mode so as to maintain higher encoding efficiency by sacrificing the speed of H.264/AVC encoder ...
Hui Su
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Fast inter mode decision exploiting intra-block similarity in HEVC

, 2019
Duvar, Ramazan (Dogus Author)Video coding standards mainly aim to decrease bit-rate to be transmitted while maintaining video quality at a certain level. Mode decision used in inter- and intra-prediction stages is a vital component of video coding and is
Akbulut, Orhan, Duvar, Ramazan, Urhan, Oğuzhan   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Projector Model for Efficient List-Mode Reconstruction in PET Scanners with Parallel Planar Detectors [PDF]

, 2011
We have developed a new projector model specifically tailored for fast list-mode tomographic reconstructions in Positron emission tomography (PET) scanners with parallel planar detectors.
Sportelli, Giancarlo, Guerra Gutiérrez, Pedro, Andres Santos, Santos Lleo, Andres de, Pedro Guerra, Guerra, P, Juan E. Ortuno, Giancarlo Sportelli, Ortuño Fisac, Juan Enrique, Santos, A., Ortuno, JE   +10 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source