Results 101 to 110 of about 805,683 (297)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
IEEE AccessThis paper presents a low-noise current-squared delta-sigma-modulation boost converter suitable for low-voltage wireless sensor networks with transient-accelerated techniques. There are two current-controlled loops and two voltage-controlled loops in the
Jiann-Jong Chen +4 more
doaj +1 more source
A Fast Transient Adaptive On-Time Controlled BUCK Converter with Dual Modulation. [PDF]
Micromachines (Basel), 2023 Sun M +5 more
europepmc +1 more source
Probing the origin of fluorescence quenching of graphene-porphyrin hybrid material [PDF]
, 2012 We report transient absorption spectroscopic studies on the hybrid material composed of porphyrin molecules covalently attached to graphene for investigating the mechanism underlying the reported fluorescence quenching of porphyrin in the hybrid [1 ...
Browne, W.R. +5 more
core +1 more source
Supergiant Fast X-ray Transients
, 2011 The phenomenology of a subclass of High Mass X-ray Binaries hosting a blue supergiant companion, the so-called Supergiant Fast X-ray Transients (SFXTs), is reviewed. Their number is growing, mainly thanks to the discoveries performed by the INTEGRAL satellite, then followed by soft X-rays observations (both aimed at refining the source position and at ...
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Special Asynchronous Dynamometer Designed for Fast Transient Phenomena
Advances in Electrical and Electronic Engineering, 2006 This paper is focused on measurement of output of the rotary electromechanic machines, i.e. torque and speed. Special attention is paid to the torque measurement under transient phenomena.
Bohumil Skala, Jiri Fort, Lucie Sykorova
doaj
DRAFTS: A Deep-learning-based Radio Fast Transient Search Pipeline
The Astrophysical Journal Supplement SeriesThe detection of fast radio bursts (FRBs) in radio astronomy is a complex task due to the challenges posed by radio-frequency interference and signal dispersion in the interstellar medium.
Yong-Kun Zhang +7 more
doaj +1 more source
Zero overshoot and fast transient response using a fuzzy logic controller [PDF]
, 2011 In some industrial process control systems it is desirable not to allow an overshoot beyond the setpoint or a threshold, this could be a safety constraint or the requirement of the system.
Mehrdadi, Bruce, Saeed, Bakhtiar I.
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source