Results 61 to 70 of about 864,998 (268)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Cultivation of Fastidious Bacteria by Viability Staining and Micromanipulation in a Soil Substrate Membrane System [PDF]

Applied and Environmental Microbiology, 2009
ABSTRACT Soil substrate membrane systems allow for microcultivation of fastidious soil bacteria as mixed microbial communities. We isolated established microcolonies from these membranes by using fluorescence viability staining and micromanipulation.
B C, Ferrari, M R, Gillings
openaire   +2 more sources

Fluorescence characterization of clinically-important bacteria [PDF]

, 2013
Healthcare-associated infections (HCAI/HAI) represent a substantial threat to patient health during hospitalization and incur billions of dollars additional cost for subsequent treatment.
Jan-Peter Muller, Brody, James P, Roberts Tom A., Lewis R Dartnell, Dartnell, Lewis R., Muller, J-P., Muller, J.P., Tom A Roberts, Muller, JP, Moore, G, Roberts, T.A., Dartnell Lewis R., Ginny Moore, Moore, Ginny, Dartnell, LR, Ward, J.M., Muller Jan-Peter, Moore Ginny, Ward, John M., Moore, G., Ward John M., Roberts, Tom A., Ward, JM, Roberts, TA, Dartnell, L.R., John M Ward   +25 more
core   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Potato Zebra Chip: An Overview of the Disease, Control Strategies, and Prospects

Frontiers in Microbiology, 2021
Potato (Solanum tuberosum L.) is an important food crop worldwide. As the demand for fresh and processed potato products is increasing globally, there is a need to manage and control devastating diseases such as zebra chip (ZC).
Victoria Mora, Manikandan Ramasamy, Mona B. Damaj, Sonia Irigoyen, Veronica Ancona, Freddy Ibanez, Freddy Ibanez, Carlos A. Avila, Carlos A. Avila, Kranthi K. Mandadi, Kranthi K. Mandadi   +10 more
doaj   +1 more source

Evaluation of a New Method for Susceptibility Testing against Fastidious and Unusual Bacteria

Journal of the Japanese Association for Infectious Diseases, 1998
The susceptibilities of 154 clinical isolates of fastidious and unusual bacteria were determined by the Etest, and were compared with the MICs for these strains obtained by the agar dilution method. Antimicrobial agents; benzylpenicillin, ampicillin, cefotaxime, imipenem, erythromycin, clindamycin and minocycline were used in this study.
KAWAKAMI, Sayoko, ONO, Yasuo, KATO, Junko, MIYAZAWA, Yukihisa   +3 more
openaire   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

First case of Francisella bacteraemia in Western Australia

New Microbes and New Infections, 2015
Francisella species are Gram-negative, nonmotile, pleomorphic coccobacilli, facultative intracellular fastidious bacteria. We report the isolation of a Francisella-like species from a blood culture collected from a 44-year-old bacteraemic patient in ...
Max Aravena-Román, Adam Merritt, Timothy J.J. Inglis   +2 more
doaj   +1 more source

A wide spectrum of fastidious and ampicillin-susceptible bacteria dominate in animal-caused wounds [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2016
The main purpose of this study was to assess the actual occurrence of Gram-negative oxidase-positive bacteria (GNOP) in human wounds caused by animals, mostly cat and dog bites and scratches, and with signs of infection. We report a prospective series of 92 wound samples.
Gustavsson, O., Johansson, A. V., Monstein, Hans-Jurg, Nilsson, Lennart E, Bredberg, A.   +4 more
openaire   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source