Results 51 to 60 of about 14,556 (244)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

First case of Francisella bacteraemia in Western Australia

New Microbes and New Infections, 2015
Francisella species are Gram-negative, nonmotile, pleomorphic coccobacilli, facultative intracellular fastidious bacteria. We report the isolation of a Francisella-like species from a blood culture collected from a 44-year-old bacteraemic patient in ...
Max Aravena-Román, Adam Merritt, Timothy J.J. Inglis   +2 more
doaj   +1 more source

Potato Zebra Chip: An Overview of the Disease, Control Strategies, and Prospects

Frontiers in Microbiology, 2021
Potato (Solanum tuberosum L.) is an important food crop worldwide. As the demand for fresh and processed potato products is increasing globally, there is a need to manage and control devastating diseases such as zebra chip (ZC).
Victoria Mora, Manikandan Ramasamy, Mona B. Damaj, Sonia Irigoyen, Veronica Ancona, Freddy Ibanez, Freddy Ibanez, Carlos A. Avila, Carlos A. Avila, Kranthi K. Mandadi, Kranthi K. Mandadi   +10 more
doaj   +1 more source

Evaluation of a New Method for Susceptibility Testing against Fastidious and Unusual Bacteria

Journal of the Japanese Association for Infectious Diseases, 1998
The susceptibilities of 154 clinical isolates of fastidious and unusual bacteria were determined by the Etest, and were compared with the MICs for these strains obtained by the agar dilution method. Antimicrobial agents; benzylpenicillin, ampicillin, cefotaxime, imipenem, erythromycin, clindamycin and minocycline were used in this study.
KAWAKAMI, Sayoko, ONO, Yasuo, KATO, Junko, MIYAZAWA, Yukihisa   +3 more
openaire   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Temporal variability of human vaginal bacteria and relationship with bacterial vaginosis.

PLoS ONE, 2010
BackgroundLittle is known about short-term bacterial fluctuations in the human vagina. This study used PCR to assess the variability in concentrations of key vaginal bacteria in healthy women and the immediate response to antibiotic treatment in women ...
Sujatha Srinivasan, Congzhou Liu, Caroline M Mitchell, Tina L Fiedler, Katherine K Thomas, Kathy J Agnew, Jeanne M Marrazzo, David N Fredricks   +7 more
doaj   +1 more source

High Prevalence of Fastidious Bacteria in 1520 Cases of Uveitis of Unknown Etiology

Medicine, 2008
The etiologic evaluation of uveitis is frequently unsuccessful when noninvasive methods are used. We conducted a prospective study to evaluate systematic screening for pathogens of uveitis. All patients with uveitis referred to the participating tertiary ophthalmology departments from January 2001 to September 2007 underwent intraocular and serum ...
Michel, Drancourt, Pierre, Berger, Céline, Terrada, Bahram, Bodaghi, John, Conrath, Didier, Raoult, Phuc, LeHoang   +6 more
openaire   +2 more sources

A wide spectrum of fastidious and ampicillin-susceptible bacteria dominate in animal-caused wounds [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2016
The main purpose of this study was to assess the actual occurrence of Gram-negative oxidase-positive bacteria (GNOP) in human wounds caused by animals, mostly cat and dog bites and scratches, and with signs of infection. We report a prospective series of 92 wound samples.
Gustavsson, O., Johansson, A. V., Monstein, Hans-Jurg, Nilsson, Lennart E, Bredberg, A.   +4 more
openaire   +3 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source