Results 201 to 210 of about 846,990 (289)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Factors associated with fasting time in pediatric patients hospitalized for surgery. [PDF]

Rev Col Bras Cir
Naspitz L, Oliveira FLC, Souza RL, Konstantyner T.   +3 more
europepmc   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Safety of long vs. short fasting after ESD/STER for esophageal tumors ≤ 2 cm: a propensity score-matching study. [PDF]

BMC Gastroenterol
Li K, Liao F, Chen T, Zhu Z, Pan X, Long S, Li G, Zhou X, Chen Y, Zhu Y, Shu X.   +10 more
europepmc   +1 more source

Bayesian Estimation Improves Prediction of Outcomes After Epilepsy Surgery

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We estimated the statistical power of studies predicting seizure freedom after epilepsy surgery. We extracted data from a Cochrane meta‐analysis. The median power across all studies was 14%. Studies with a median sample size or less (n ≤ 56) and a statistically significant result exaggerated the true effect size by a factor of 5.4, while the ...
Adam S. Dickey, Vineet Reddy, Ammar A. Rashied, Nigel P. Pedersen, Robert T. Krafty   +4 more
wiley   +1 more source

Ramadan fasting and hematological disorders: clinical considerations, risks, and management strategies. [PDF]

Clin Hematol Int
Nasiri A, Alahmadi A, Alshammari M, Alabiri R, Samarkandi S, Alfattah H, Alqahtani R, Alzahrani T, Samarkandi H, Habash A, Alsolamy E, Al Ghethber H, Alkharras R, Makhdoum G, Saleh MFM, Hanbali A, El Fakih R, Alzahrani H, Alahmari A, Aljurf M.   +19 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging. [PDF]

Aging Cell
Milan M, Troyano-Rodriguez E, Ihuoma J, Negri S, Rudraboina R, Kosmider A, Awasthi S, Balasubramanian P, Conley S, Yabluchanskiy A, Csiszar A, Ungvari Z, de Cabo R, Tarantini S.   +13 more
europepmc   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Postprandial 2-h glucose tolerance is associated with diabetes diagnosis, diabetes mortality, and cardiovascular mortality. [PDF]

Sci Rep
Wang Y, Fang Y, Yang G, Prattichizzo F, Ceriello A.   +4 more
europepmc   +1 more source