Results 51 to 60 of about 575,766 (316)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Real-World Study in Patients with Type 2 Diabetes Treated with Gliclazide Modified Release during Fasting in Gulf Cooperation Council Countries: An Analysis from the International DIA-RAMADAN Study

Dubai Diabetes and Endocrinology Journal, 2022
Introduction: The safety and effectiveness of gliclazide modified release (MR) in patients with type 2 diabetes mellitus (T2DM) who fasted during Ramadan were previously published.
Mohamed Hassanein, Saud Al Sifri, Fatheya Al Awadi, Thamer Alessa, Ashraf Shaaban   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Hypoglycemia compensation mechanisms in dry fasting

Metabolism Open
Background: Dry fasting (DF) presents three primary risks: hypovolemia, hypertonicity, and hypoglycemia. The first two have been shown to be effectively compensated, and the respective mechanisms have been studied.
Ioannis-Eleemon Papagiannopoulos-Vatopaidinos, Maria I. Papagiannopoulou, Eleni N. Dotsika   +2 more
doaj   +1 more source

The Strong Antioxidant Sheep/Goat Whey Protein Protects Against mTOR Overactivation in Rats: A Mode of Action Mimicking Fasting

Antioxidants, 2019
Whey protein, a by-product of the cheese industry, can be putatively used as a functional food due to its beneficial health properties. The main objective of the present study was to assess in vivo the effect of a sheep/goat whey protein on the plasma ...
Efthalia Kerasioti, Aristidis Veskoukis, Christina Virgiliou, Georgios Theodoridis, Ioannis Taitzoglou, Dimitrios Kouretas   +5 more
doaj   +1 more source

Variability among Physicians in Risk Stratification for People with Diabetes during Ramadan Fasting

Dubai Diabetes and Endocrinology Journal, 2023
Introduction: A novel clinical calculator was developed to assist physicians in classifying the risk for individuals with diabetes planning to observe fasting during the holy month of Ramadan.
Bachar Afandi, Mohamed Hassanein, Shehla Shaikh, Gamal Ibrahim, Monira Alarouj   +4 more
doaj   +1 more source

Could fasting be a tool for political healing in Israel? [PDF]

, 2023
The head of an Orthodox Jewish group had called for fasting in response to the polarisation in Israeli society over judicial ...
Jangid, Khinvraj
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Put on the sidelines of palliative care: a qualitative study of important barriers to GPs’ participation in palliative care and guideline implementation in Norway

Scandinavian Journal of Primary Health Care
Background Demographic changes, the evolvement of modern medicine and new treatments for severe diseases, increase the need for palliative care services. Palliative care includes all patients with life-limiting conditions, irrespective of diagnosis.
Anne Fasting, Irene Hetlevik, Bente Prytz Mjølstad   +2 more
doaj   +1 more source

The effect of Ramadan fasting on non-alcoholic fatty liver disease (NAFLD) patients [PDF]

Journal of Fasting and Health, 2015
Purpose: The aim of this study was to compare biochemical tests, body composition and anthropometric parameters in Nonalcoholic Fatty Liver Disease (NAFLD) patients before and after Ramadan fasting. Methods: fifty NAFLD patients including 33 males and 17
Seyed Mostafa Arabi, Sudiyeh Hejri Zarifi, Mohsen Nematy, Mohammad Safarian   +3 more
doaj   +1 more source