Ramadan Fasting in a Patient with Chronic Myeloid Leukemia Receiving Nilotinib as Upfront
Case Reports in Oncology, 2020 Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm classically described as triphasic disease: chronic, accelerated, and blast crisis. There are many unmet needs and unanswered questions about CML.
Husam N. Al-Dubai +4 more
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Perspectives on Fasting in Islam [PDF]
, 2012 This is an article prepared for an unpublished collection on the anthropology of fasting.
Lindholm, Charles
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Birthweight and risk markers for type 2 diabetes and cardiovascular disease in childhood: the Child Heart and Health Study in England (CHASE). [PDF]
, 2015 AIMS/HYPOTHESIS: Lower birthweight (a marker of fetal undernutrition) is associated with higher risks of type 2 diabetes and cardiovascular disease (CVD) and could explain ethnic differences in these diseases. We examined associations between birthweight
A Bavdekar +52 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Preliminary evidence supports circulating microRNAs as prognostic biomarkers for type 2 diabetes. [PDF]
, 2017 Background:Circulating microRNAs are emerging as potential prognostic biomarkers for the development of type 2 diabetes. However, microRNAs are also associated with complications from impaired glucose metabolism (e.g. endothelial cell function).
Allen, IE +5 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
TV 2 konstruerer en håndballkriger – Kjønnede og symbolske medierepresentasjoner av herrehåndball
Norsk Medietidsskrift, 2009 : The article explores a gendered perspective on Norwegian TV-media production and representation of mens team handball. A discourse analysis, influenced by Connell (2005), Bourdieu (1997) and Messner (2002), is applied and the concepts anomaly
Kari Fasting, Trygve Beyer Broch
doaj
Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. [PDF]
, 2018 The extracellular matrix is a master regulator of tissue homeostasis in health and disease. Here we examined how the small, leucine-rich, extracellular matrix proteoglycan decorin regulates cardiomyocyte metabolism during fasting in vivo.
Gubbiotti, Maria A. +4 more
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Effect of Progressive Weight Loss on Lactate Metabolism: A Randomized Controlled Trial. [PDF]
, 2018 OBJECTIVE:Lactate is an intermediate of glucose metabolism that has been implicated in the pathogenesis of insulin resistance. This study evaluated the relationship between glucose kinetics and plasma lactate concentration ([LAC]) before and after ...
Chondronikola, Maria +7 more
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AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source