Results 51 to 60 of about 346,352 (306)

Genetic selection for high and low fasting blood glucose levels in mice. I. Fasting blood glucose levels, glucose tolerance and isolated tissue studies [PDF]

Diabetologia, 1973
Swiss-Hauschka mice have been selected for high (HG) and low (LG) fasting blood glucose (FBG) levels for four generations. All matings were brother to sister. Differences in mean FBG levels have remained relatively constant (20 to 30 mg%) between the two lines since initiation of selection ...
R E, Gleason, P L, Poffenbarger, R L, Lavine   +2 more
openaire   +2 more sources

Screening for hyperglycaemia in pregnancy : a rapid update for the National Screening Committee [PDF]

, 2010
Background Screening for gestational diabetes has long been a controversial topic. A previous Health Technology Assessment (HTA) report reviewed literature on screening for gestational diabetes mellitus (GDM) and assessed the case for screening against ...
P Royle, C Clar, Henderson, R., Cummins, E., N Waugh, Henderson, Rob, D Hadden, Royle, P., Clar, C., Lindsay, R. (Robert), Hadden, D. R., Cummins, E. (Ewen), HASH(0x55a67fd05ca0), E Cummins, Pearson, D., Waugh, Norman, Pearson, Donald, Hadden, D., R Henderson, Lindsay, R., D Pearson, Royle, Pamela, Waugh, N., R Lindsay   +23 more
core   +1 more source

Sex-specific differences in the relationship between fasting plasma glucose and carotid plaque in a cardiovascular high-risk population: a cross-sectional study

Frontiers in Endocrinology
BackgroundDespite extensive research on the epidemiological risk factors linking diabetes and carotid plaques, evidence regarding sex-specific differences remains scarce.
Mengjie Xu, Kai Xu, Weiguo Lin, Ruixue Sun, Shaorong Yan, Xiaoshu Chen, Yuzhan Lin   +6 more
doaj   +1 more source

Comparison of Three Types of Low-calorie Diets on Blood Glucose and Lipid Control in Diabetic Patients [PDF]

JLUMHS, 2018
BACKGROUND: Serum glucose levels can get close to a normal level by an appropriate diet. The present study aims to investigate the effect of low-calorie diets (1200, 1500, 1800 Kcal) on glucose and lipid levels, and HbA1C serum levels of newly diagnosed ...
Zoleika Moazezi, Seyed Reza Hosseini, Parvin Sajadi Kaboudi , Soheil Ebrahimpour, Mojgan Abbaszadeh Marzbali   +4 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Phenotypic and Genetic Evidence for a More Prominent Role of Blood Glucose than Cholesterol in Atherosclerosis of Hyperlipidemic Mice

Cells, 2022
Hyperlipidemia and type 2 diabetes (T2D) are major risk factors for atherosclerosis. Apoe-deficient (Apoe−/−) mice on certain genetic backgrounds develop hyperlipidemia, atherosclerosis, and T2D when fed a Western diet.
Ashley M. Abramson, Lisa J. Shi, Rebecca N. Lee, Mei-Hua Chen, Weibin Shi   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Low testosterone level increases fasting blood glucose level in adult males [PDF]

Universa Medicina, 2012
Background Total testosterone (TT) levels in males decrease with age. There has been a vigorous debate on the extent to which low testosterone causally contributes to diabetes and its complications.
Suweino, ML Edy Parwanto, David Tjahjadi
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source