Results 61 to 70 of about 346,352 (306)

A Bivariate Genome-Wide Approach to Metabolic Syndrome STAMPEED Consortium [PDF]

, 2010
OBJECTIVE The metabolic syndrome (MetS) is defined as concomitant disorders of lipid and glucose metabolism, central obesity, and high blood pressure, with an increased risk of type 2 diabetes and cardiovascular disease.
O'Reilly, Paul F., David J. Couper, Marjo-Riitta Jarvelin, Mathias, Rasika A., Sun, Y. V., Becker, DM, Zhang, Q., Psaty, Bruce M., Dhananjay Vaidya, Assimes, Themistocles L., Rotter, Jerome I, Cashell Jaquish, Becker, LC, McCarthy, Mark I, Boerwinkle, E., Franceschini, Nora, O'Reilly, P. F., O'Reilly, Paul F, Feitosa, MF, Hartikainen, A.-L., Yanek, L., Knowles, JW, Bruce M. Psaty, Becker, Diane M, Mathias, RA, Lewis C. Becker, Goodarzi, Mark O., Kardia, Sharon LR, Glazer, NL, Themistocles L. Assimes, Kraja, Aldi T, Couper, D. J., Mathias, Rasika A, Couper, DJ, Kardia, SL, Kullo, I. J., Rasika A. Mathias, Province, Michael A., Guo Li, Borecki, IB, Absher, Devin, Borecki, Ingrid B., Chakravarti, A, Iribarren, C., Yanek, Lisa, Kari E. North, Jaquish, Cashell, O’Reilly, Paul F, Sovio, U., Becker, D. M., Sun, Yan V, Kraja, AT, Paul F. O’Reilly, Yii-Der Ida Chen, Lisa Yanek, Vaidya, D., Quertermous, Thomas, Chen, Yii-Der Ida, Leena Palotie, Sun, Yan V., Boerwinkle, Eric, Aldi T. Kraja, Goodarzi, Mark O, Pankow, JS, Talin Haritunians, Psaty, Bruce M, Palotie, L., Boerwinkle, E, Zhang, Q, Becker, L. C., Kral, Brian, Sovio, U, Feitosa, Mary F., Haritunians, T., North, Kari E., Haritunians, Talin, Brian Kral, Quertermous, T., Chen, Y.-d. I., Hartikainen, Anna-Liisa, Feitosa, Mary F, Chakravarti, A., Jarvelin, Marjo-Riitta, Hartikainen, AL, Mark O. Goodarzi, Diane M. Becker, Chakravarti, Aravinda, Sharon L.R. Kardia, Mary F. Feitosa, Palotie, L, Couper, David J., Anna-Liisa Hartikainen, Borecki, I. B., Nora Franceschini, Jarvelin, MR, North, Kari E, Knowles, Joshua W, Pankow, James S, Jerome I. Rotter, Couper, David J, Franceschini, N., McCarthy, M. I., Iribarren, C, Psaty, BM, Yanek, L, Vaidya, Dhananjay, Psaty, B. M., Kral, B, Becker, Lewis C, Kral, B., Michael A. Province, Ingrid B. Borecki, Chen, YD, Goodarzi, M. O., Glazer, N. L., Becker, Lewis C., Palotie, Leena, Jaquish, C., Kraja, Aldi T., Glazer, Nicole L, Kullo, IJ, Thomas Quertermous, Kullo, Iftikhar J, Joshua W. Knowles, Carlos Iribarren, Zhang, Qunyuan, Quertermous, T, Ulla Sovio, Li, Guo, Haritunians, T, Mathias, R. A., Jarvelin, M.-r., Sovio, Ulla, Qunyuan Zhang, Iftikhar J. Kullo, Province, Michael A, Rotter, J. I., Pankow, James S., Province, MA, McCarthy, MI, James S. Pankow, Knowles, J. W., Borecki, Ingrid B, Li, G, Eric Boerwinkle, Becker, Diane M., Kardia, Sharon L. R., Glazer, Nicole L., O'Reilly, PF, Sun, YV, North, K. E., Li, G., Mark I. McCarthy, Absher, D, Iribarren, Carlos, Vaidya, D, Absher, D., Feitosa, M. F., Franceschini, N, Aravinda Chakravarti, Knowles, Joshua W., Assimes, Themistocles L, Yan V. Sun, Kardia, S. L. R., Pankow, J. S., Rotter, Jerome I., Assimes, TL, Devin Absher, McCarthy, Mark I., North, KE, Assimes, T. L., Goodarzi, MO, Province, M. A., Jaquish, C, Nicole L. Glazer, Rotter, JI, Kraja, A. T., Kullo, Iftikhar J.   +177 more
core   +1 more source

A Hepatocyte FOXN3-α Cell Glucagon Axis Regulates Fasting Glucose

Cell Reports, 2018
Summary: The common genetic variation at rs8004664 in the FOXN3 gene is independently and significantly associated with fasting blood glucose, but not insulin, in non-diabetic humans.
Santhosh Karanth, J.D. Adams, Maria de los Angeles Serrano, Ezekiel B. Quittner-Strom, Judith Simcox, Claudio J. Villanueva, Lale Ozcan, William L. Holland, H. Joseph Yost, Adrian Vella, Amnon Schlegel   +10 more
doaj   +1 more source

Correlation of Serum Uric Acid and Lipid Profile in Patients with Type 2 Diabetes Mellitus

Journal of Nepal Health Research Council, 2023
Background: Diabetes complication poses a new challenge in Nepal as the disease is becoming endemic. Identifying risk factor for diabetes can be an essential step in preventing complication related to diabetes.
Pragya Malla, Madhav Prasad Khanal, Asmita Pokhrel, Bishesh Sah, Sonam Pathak, Anukul Subedi, Srijana Sapkota   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Forest Plot: Fasting Blood Glucose. [PDF]

, 2015
Forest Plot: Fasting Blood Glucose.
Nicola J. Roberts (707725), Jan Pringle (707722), Lindsay Govan (698950), Joanne Booth (707724), Maggie Lawrence (707721), Susan Kerr (707723)   +5 more
core   +1 more source

Evaluation of glycemic abnormalities in children and adolescents with β-thalassemia major

Egyptian Pediatric Association Gazette, 2021
Background The quality of life of B-thalassemia major (β-TM) patients has improved with the use of frequent blood transfusions. However, this leads to chronic iron overload with its sequelae, as prediabetes and diabetes mellitus.
Aliaa M. Diab, Ghada S. Abdelmotaleb, Khaled Abdel-Azim Eid, Enas Sebaey S. Mostafa, Eman Sabry Ahmed   +4 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Clinical implication of fasting and post-challenged plasma glucose in diagnosis of diabetes mellitus [PDF]

, 2017
Fasting plasma glucose (FPG) is the preferred test in diagnosis of diabetes mellitus (DM) to 2-h post-challenged plasma glucose (2hPG). There is little information available on the comparison between FPG and 2hPG diagnostic criteria.
Huang, Jean;Ou, Horng-Yih;Karnchanasorn, Rudruidee;Samoa, Raynald;Chuang, Lee-Ming;Chiu, Ken C.;Feng, Wei, 莊立民   +1 more
core   +1 more source

Impact of prenatal famine exposure on adulthood fasting blood glucose level

Scientific Reports, 2022
In the past decade, in low-income countries, there have been a rapid rise in prevalence of diabetes among adult population. Hence, understanding the context specific drivers of this change including the impacts of childhood nutrition adversaries on adult
Kalkidan Hassen Abate, Getachew Arage, Habtamu Hassen, Jemal Abafita, Tefera Belachew   +4 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source