Results 61 to 70 of about 476,185 (305)

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations [PDF]

open access: yesDiabetes, 2016
Genome-wide association studies (GWAS) have successfully identified genetic loci associated with glycemic traits. However, characterizing the functional significance of these loci has proven challenging. We sought to gain insights into the regulation of fasting insulin and fasting glucose through the use of gene expression microarray data from ...
Chen, BH   +27 more
openaire   +2 more sources

Fasting blood glucose level in patients presenting with erectile dysfunction

open access: yesSanamed, 2021
Introduction: An increase in diabetes mellitus (DM) causes different complaints and concerns. This retrospective cross-sectional study aimed to test fasting blood glucose (FBG) levels in patients presenting with erectile dysfunction (ED). Materials and Methods: The patients included in the study were divided into two groups.
Aysun Isiklar, Sibel Ocak Serin
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

FOXN3 Regulates Hepatic Glucose Utilization

open access: yesCell Reports, 2016
A SNP (rs8004664) in the first intron of the FOXN3 gene is associated with human fasting blood glucose. We find that carriers of the risk allele have higher hepatic expression of the transcriptional repressor FOXN3.
Santhosh Karanth   +4 more
doaj   +1 more source

Effect of Drug Information Service on Clinical Outcome of Patients with Type 2 Diabetes Mellitus in Padang, Indonesia

open access: yesBorneo Journal of Pharmacy, 2022
Type 2 diabetes mellitus (T2DM) has been a health burden worldwide, including Indonesia. However, T2DM therapy needs a long and complex process, which patients often do not favor, thus making them does not take medications as instructed and negatively ...
Lailaturrahmi Lailaturrahmi   +3 more
doaj   +1 more source

Antidiabetic effect of Tibetan medicine Tang-Kang-Fu-San on high-fat diet and streptozotocin-induced type 2 diabetic rats [PDF]

open access: yes, 2017
The aim of this study was to investigate the antidiabetic effects of a Tibetan medicine, Tang-Kang-Fu-San (TKFS), on experimental type 2 diabetes mellitus (T2DM) rats and to explore its underlying mechanisms.
Duan, Bailu   +8 more
core   +3 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Effectiveness of exclusive self-monitoring of fasting capillary blood glucose in the treatment of diabetes

open access: yesActa Scientiarum. Health Sciences, 2015
The study aims to analyze the efficacy of the exclusive self-monitoring of the fasting capillary blood glucose in the control and treatment of diabetic patients.
Henrique Amancio Ferreira   +4 more
doaj   +1 more source

Screening of patients with tuberculosis for diabetes mellitus in China. [PDF]

open access: yes, 2012
Objective  There is a high burden of both diabetes (DM) and tuberculosis (TB) in China, and this study aimed to assess feasibility and results of screening patients with TB for DM within the routine healthcare setting of six health facilities.
Chi, J   +14 more
core   +2 more sources

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