Results 191 to 200 of about 168,137 (259)

Pediatric Psoriasis: A Peek into the Comorbidity Profile.

Indian J Dermatol
Gupta S, Goel S, Chopra D, Malhan S, Sidhu AS.   +4 more
europepmc   +1 more source

Aescin and rutin mitigate hyperthyroidism-induced multisystem dysfunction via antioxidant and anti-inflammatory mechanisms in a rat model. [PDF]

Sci Rep
Makadi MA, Ibrahim IA, Bahr HI, Elkelish A, Oumarou Z, Rudayni H, Ahmed AAM, Mahmoud YK.   +7 more
europepmc   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Efficacy of Orlistat on Cardiometabolic Indices in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A GRADE-Assessed Systematic Review and Meta-Analysis of RCTs. [PDF]

Curr Ther Res Clin Exp
Karimi M, Pourfaraji SMA, Parhizkar Roudsari P, Pirzad S.   +3 more
europepmc   +1 more source

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source

Study of Platelet Parameters Among Dyslipidaemic Patients. [PDF]

Cureus
Hariharan P, Shanmugam SG, Priyathersini N, Subramanian P S M.   +3 more
europepmc   +1 more source

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair

Advanced Science, EarlyView.
Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
wiley   +1 more source

Reduced circulating STOX1 is associated with inflammatory cytokines and insulin resistance in obese individuals: a cross-sectional study. [PDF]

Front Nutr
Wang Y, Xiang M, Jiang X, Shuai M, Jian L, Geng S.   +5 more
europepmc   +1 more source

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo, Dohyeon Kim, Junhyuk Song, Sun‐Young Kim, Youngju Son, Afia Tasnim Rahman, Sangyong Jon   +6 more
wiley   +1 more source

Metabolic effects of metyrapone treatment in patients with mild autonomous cortisol secretion: a prospective proof-of-concept trial. [PDF]

EClinicalMedicine
Niziolek H, Just I, Tosin A, Baumgartner C, Körmöczi K, Bellach L, Fellinger P, Beiglböck H, Skuciova H, Gericke G, Lässer S, Luger A, Trattnig S, Kautzky-Willer A, Schernthaner-Reiter MH, Kiefer FW, Vila G, Scherer T, Leutner M, Krssak M, Krebs M, Wolf P.   +21 more
europepmc   +1 more source