Results 41 to 50 of about 168,137 (259)

A case of acanthosis nigricans in a HIV-infected patient [PDF]

, 2020
Background: To date, very little information is available concerning the relationship between acanthosis nigricans (AN) and infection with human immunodeficiency virus type 1 (HIV-1).
De Vincentiis, Ludovica, Di Paolo, Marcello, Iacovelli, Alessandra, Mezzaroma, Ivano, Palange, Paolo, Soda, Giuseppe   +5 more
core   +1 more source

FASTING LIPID PROFILE AND DISEASE SEVERITY IN SEPSIS PATIENTS

International Journal of Medical and Biomedical Studies, 2019
Background: During an infection and inflammation many cytokines are released. This produces many changes in plasma lipids and lipoprotein concentration. Methods: This was a prospective observational study. Patients with age greater than 18 years and satisfying the criteria for sepsis according to International guidelines for management of severe ...
Manpreet Kaur, Pramod Sood
openaire   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Fasting Lipid Profile and Disease Severity in Sepsis Patients

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2017
Introduction: Sepsis is a systemic inflammatory response syndrome that has a proven or suspected microbial aetiology. Sepsis carries significant morbidity and mortality. During sepsis many changes occur in plasma lipids and lipoproteins. These changes help in fighting inflammation and contribute to host defence.
P Sunayana, B Renymol, N R Ambili
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Fasting versus Non-fasting Lipid profile in the clinical practice

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2018
There are pros and cons doing fasting and random non-fasting lipid profile test. However, when we consider cardio vascular risk, non-fasting lipid test more reliable than fasting test. In current practice, using fasting lipid profile was challenged in 2007 by two studies that showed that random non-fasting triglyceride (TG) could be superior than ...
openaire   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Association between circulating adiponectin levels and polycystic ovarian syndrome [PDF]

, 2014
Background: Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (
Khan, Naveed Ali, Mirza, Saeed Mirza, Qureshi, Masood Anwar, Shafique, Kashif, Shaikh, Abdul Rauf   +4 more
core   +3 more sources

Association between serum Mg2+ concentrations and cardiovascular organ damage in a cohort of adult subjects [PDF]

, 2020
Magnesium (Mg2+) levels are associated with insulin resistance, hypertension, atherosclerosis, and type 2 diabetes (T2DM). We evaluated the clinical utility of physiological Mg2+ in assessing subclinical cardiovascular organ damage including increased ...
Andreozzi, F., Averta, C., Fiorentino, T. V., Mancuso, E., Mannino, G. C., Miceli, S., Perticone, F., Perticone, M., Rubino, M., Sciacqua, A., Sesti, G., Spiga, R., Succurro, E.   +12 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source