Results 41 to 50 of about 35,955 (275)
Intraparenchymal Neuromonitoring of Cerebral Fat Embolism Syndrome
Critical Care Explorations, 2021 Objectives:. We aimed to characterize the cerebrovascular physiology of cerebral fat embolism using invasive multimodal neuromonitoring. Data Sources:. ICU, Vancouver General Hospital, Vancouver, BC, Canada. Study Selection:. Case report. Data Extraction:
Ryan Leo Hoiland, PhD +3 more
doaj +1 more source
Angewandte Chemie, EarlyView.Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources
Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth +8 more
wiley +1 more source
LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models
Advanced Functional Materials, EarlyView.This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti +27 more
wiley +1 more source
Critical Care and Resuscitation, 1999 To review the pathophysiology and management of patients with clinical manifestations of fat embolism.A review of studies reported from 1976 to 1998 and identified through a MEDLINE search of the literature on fat embolism and fat embolism syndrome.Fat embolism occurs when bony or soft tissue trauma has caused fat to enter the circulation, or in ...
P, Glover, L I, Worthley
openaire +2 more sources
Isolated Cerebral Fat Embolism After Lower Extremity Fracture: Case Report
Türk Yoğun Bakim Derneği Dergisi, 2015 Fat embolism syndrome (FES) is characterized with petechiae, mental confusion, and respiratory failure, occurs generally after lower extremity long bone fractures or orthopedic surgery within 24-72 hours.
Canan Yılmaz +5 more
doaj +1 more source
Annals of Internal Medicine: Clinical Cases, 2023 Sickle cell disease is characterized by episodic vaso-occlusive events triggered by a combination of inflammation, increased adhesion to vascular endothelial cells, and activation of hemostasis.
Zachary Buxo +3 more
doaj +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Influence of Body Composition on Arterial Stiffness in Middle-Aged Adults: Healthy UAL Cross-Sectional Study [PDF]
, 2019 Background and objectives: Several anthropometric and body composition parameters have been linked to arterial stiffness (AS) as a biomarker of cardiovascular disease. However, little is known about which of these closely related factors is more strongly
Alcaraz Ibáñez, Manuel +4 more
core +1 more source