Results 71 to 80 of about 815,018 (356)
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Body composition analysis on elderly living in nursing homes [PDF]
Body composition is a good indicator of an individual’s health and physical status. In addition to total body fat, fat distribution is a major risk factor for cardiovascular diseases and insulin resistance/diabetes in elderly.
Gültekin, Timur, Koca Özer, Başak
core +3 more sources
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Assessment of total and segmental body composition in spinal cord-injured athletes in okayama prefecture of Japan. [PDF]
This study assessed total and segmental distribution of fat mass (FM) in athletes with spinal cord injury (SCI) and examined the relationships between segmental distribution of fat mass and age, injury level, athletic history, and training load in order ...
Inukai, Yoshihide +3 more
core +2 more sources
Total Energy Expenditure and Body Composition of Children with Developmental Disabilities [PDF]
Background Obesity prevalence is increased in children with developmental disabilities, specifically in children with spina bifida and Down syndrome.
Bandini, Linda +7 more
core +1 more source
Case study of a female ocean racer: prerace preparation and nutritional intake during the Vendee Globe 2008. [PDF]
The Vendée Globe is a solo round-the-world sailing race without stopovers or assistance, a physically demanding challenge for which appropriate nutrition should maintain energy balance and ensure optimum performance.
Brightmore, A +5 more
core +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Background: Negative lifestyle trends are reflected in overweight and obese children, in which their lack of physical activity results in decreased muscle mass.
Vendula Zbořilová +2 more
doaj +1 more source
High-intensity interval training combined with vibration and dietary restriction Improves body composition and blood lipids in obese adults: a randomized trial [PDF]
This study aimed to compare the effect of high-intensity interval training (HIIT) with additional whole-body vibration (WBV) on body composition and lipid profile in obese/overweight adults on a hypocaloric diet.
López Lluch, Guillermo +4 more
core +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source

