Results 171 to 180 of about 535,411 (309)

Dietary cysteine drives body fat loss via FMRFamide signaling in Drosophila and mouse. [PDF]

open access: yesCell Res, 2023
Song T   +9 more
europepmc   +1 more source

Food diary strategies for body fat loss

open access: yesThe FASEB Journal, 2011
Campbell, Cortney Kay, Hartzler, Lynn K.
openaire   +2 more sources

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

Genome-Wide Association Study of Exercise-Induced Fat Loss Efficiency. [PDF]

open access: yesGenes (Basel), 2022
Bojarczuk A   +11 more
europepmc   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

open access: yesAdvanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu   +17 more
wiley   +1 more source

Fat in the Fifties America's First Obesity Crisis

open access: yes, 2019
Fat in the Fifties is required reading for public health practitioners and researchers, physicians, historians of medicine, and anyone concerned about weight and weight ...
Rasmussen, Nicolas ; https://orcid.org/
core  

The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Loss: A Randomized Controlled Trial. [PDF]

open access: yesNutrients
Johnson KE   +8 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

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