Results 231 to 240 of about 6,022,993 (297)

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

The MetaboHealth score enhances insulin resistance metabotyping for targeted fat loss through personalized diets: Insights from the PERSON intervention study

Morwani-Mangnani J, Bogaards FA, Umanets A, Hul GB, Gijbels A, Goossens GH, Deelen J, Beekman M, Afman L, Blaak EE, Slagboom PE.   +10 more
europepmc   +1 more source

Effectiveness of an intermittent fasting diet versus regular diet on fat loss in overweight and obese middle-aged and elderly people without metabolic disease: a systematic review and meta-analysis of randomized controlled trials. [PDF]

J Nutr Health Aging
Yao K, Su H, Cui K, Gao Y, Xu D, Wang Q, Ha Z, Zhang T, Chen S, Liu T.   +9 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Quercetin attenuates cisplatin-induced fat loss

European Journal of Nutrition, 2020
The major aim of the present study was to determine the effects of quercetin, a well-known flavonoid, on attenuating cisplatin (CDDP)-induced fat loss and the possible mechanisms.Tumor-bearing nude mice and tumor-free BALB/c mice were administrated with CDDP alone or in combination with quercetin by a diet containing 0.1% or 1% quercetin (LQ or HQ) or ...
Shu-Lan Yeh, Jiunn-Wang Liao, Yi-Chin Lin   +2 more
exaly   +4 more sources

Exercise training‐induced visceral fat loss in obese women: The role of training intensity and modality

Scandinavian Journal of Medicine & Science in Sports, 2020
Visceral fat loss in response to four‐cycle ergometer training regimens with explicit differences in exercise intensity and modality was compared.
Haifeng Zhang, T. K. Tong, Z. Kong, Q. Shi, Yang Liu, J. Nie   +5 more
semanticscholar   +1 more source

Regional differences in abdominal fat loss

International Journal of Obesity, 2006
This study determined if the magnetic resonance imaging (MRI) protocol used alters the estimation of change in abdominal fat with weight loss in obese type 2 diabetic women. This study also examined if there is a uniform fat loss across the abdomen.Thirty-three obese postmenopausal women with type 2 diabetes (age 50-70 years, body mass index>30 kg/m(2))
J A, Kanaley, I, Giannopoulou, L L, Ploutz-Snyder   +2 more
openaire   +2 more sources

Prostaglandins, brown fat and weight loss

Medical Hypotheses, 1989
In obesity, a situation is created in which energy intake exceeds energy expenditure. The three components of energy expenditure are resting metabolism, physical activity, and thermogenesis. Increasing attention is being paid to the role of impaired energy expenditure in obesity. Evidence indicates that impairment in activity of the sympathetic nervous
E P, Heleniak, B, Aston
openaire   +2 more sources