Results 231 to 240 of about 577,307 (266)

Microfilament‐Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice

open access: yesAdvanced Science, EarlyView.
In this study, we provided new evidence identifying multinucleated cysts as precursors for oocyte differentiation. Within these cysts, organelles migrate and aggregate to form Balbiani body (B‐body) and establish early cellular polarity. Concurrently, excess nuclei are expelled, enabling cyst‐to‐oocyte differentiation. The microfilament‐myosin II plays
Rui Xu   +7 more
wiley   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

open access: yesAdvanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu   +17 more
wiley   +1 more source

Gender and age differences in weekend eating habits: associations with fat mass percentage in a cross-sectional study. [PDF]

open access: yesFront Nutr
Gorini S   +10 more
europepmc   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

open access: yesAdvanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li   +9 more
wiley   +1 more source

Early-life exposures to phenols, parabens and phthalates and fat mass at 3 years of age in the SEPAGES cohort

open access: hybrid
Maude Colombini   +9 more
openalex   +1 more source

Oral Celastrol Micelles Forming High‐Density Lipoprotein Corona Targeting Hepatocytes for MASLD Treatment

open access: yesAdvanced Science, EarlyView.
Upon oral administration, OPDEA‐PCL/CEL micelles passed through the stomach acid intact, then quickly penetrated the intestinal mucus and transported into circulation, where they captured HDL to form a protein corona and target hepatocyte SR‐B1 receptors, inducing endocytosis.
Chang Xu   +11 more
wiley   +1 more source

Relationship Between Body Mass Index and Fat Mass Percentage with Proprioception in Children. [PDF]

open access: yesJ Funct Morphol Kinesiol
Guzmán-Muñoz E   +7 more
europepmc   +1 more source

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