Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
Fat mass index performs best in monitoring management of obesity in prepubertal children
Objective: An early and accurate recognition of success in treating obesity may increase the compliance of obese children and their families to intervention programs.
Luís Pereira‐da‐Silva +7 more
doaj +1 more source
Influence of Body Composition on Arterial Stiffness in Middle-Aged Adults: Healthy UAL Cross-Sectional Study [PDF]
Background and objectives: Several anthropometric and body composition parameters have been linked to arterial stiffness (AS) as a biomarker of cardiovascular disease. However, little is known about which of these closely related factors is more strongly
Alcaraz Ibáñez, Manuel +4 more
core +1 more source
Higher dietary flavonoid intakes are associated with lower objectively measured body composition in women: evidence from discordant monozygotic twins [PDF]
Background: Although dietary flavonoid intake has been associated with less weight gain there are limited data on its impact on fat mass and the contribution of genetic factors to this relationship has not previously been assessed.
Cassidy, Aedin +3 more
core +1 more source
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King +10 more
wiley +1 more source
Genetic Markers as Instrumental Variables:An Application to Child Fat Mass and Academic Achievement [PDF]
The use of genetic markers as instrumental variables (IV) is receiving increasing attention from economists. This paper examines the conditions that need to be met for genetic variants to be used as instruments.
Carol Propper +4 more
core
A study of body composition and its association with disease severity in stable chronic obstructive pulmonary disease patients in HUSM [PDF]
Background: COPD is not just a disease of the lungs alone; it has systemic manifestations due to the underlying pathogenesis of inflammatory reaction.
Asmee, Mohammad Faisal
core
Association of fat mass profile with natriuretic peptide receptor alpha in subcutaneous adipose tissue of medication-free healthy men: A cross-sectional study [PDF]
Background: Atrial natriuretic peptide increases lipolysis in human adipocytes by binding to natriuretic peptide receptor-A (NPRA). The aim of the current study was to examine the associations of NPRA mRNA of subcutaneous adipose tissue with fat mass ...
Dinas, Petros C +9 more
core +1 more source
Background: Percent body fat, fat mass and fat mass index are measures of body fat while fat free mass and fat free mass index measure lean mass. These measures of body composition vary with age and sex.
Nwizu SE +3 more
doaj
Background and objectives: The finding of an association between health and body composition mandated the necessity for frequent testing of body composition for all.
Ibrahim Mustafa
doaj +1 more source

