Results 271 to 280 of about 1,171,043 (349)

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Body Mass Index, Fat Volume and Outcome of Laparoscopy-Assisted Distal Gastrectomy

, 2009
Taiki Kojima, Takanori Matsui, Takanori Uemura, Yasunobu Fujimitsu, Shigehiro Kure, Hiroshi Kojima, Kazushige Misawa, Takashi Kinoshita, Michitaka Fujiwara   +8 more
openalex   +2 more sources

Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts

, 2010
Amy E. Taylor, Shah Ebrahim, Yoav Ben‐Shlomo, Richard M. Martin, Peter H. Whincup, J. W. G. Yarnell, S. Goya Wannamethee, Debbie A. Lawlor   +7 more
openalex   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

Fat-free mass index: changes and race/ethnic differences in adulthood

, 2010
Holly R. Hull, J. Thornton, J. Wang, Richard N. Pierson, Zafar U. Kaleem, F. Xavier Pi‐Sunyer, Steven B. Heymsfield, Jeanine Albu, José R. Fernández, Theodore B. VanItallie, Dympna Gallagher   +10 more
openalex   +1 more source

Genome-wide mRNA expression profiling in vastus lateralis of COPD patients with low and normal fat free mass index and healthy controls [PDF]

, 2015
Roberto Rabinovich, Ellen Drost, Jonathan Manning, Donald R. Dunbar, M. Carmen Díaz-Ramos, Ramzi Lakhdar, Ricardo Bastos, William MacNee   +7 more
openalex   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Associations of 18-Year-Old Daughters' and Mothers' Serum Leptin, Body Mass Index and DXA-Derived Fat Mass

, 2010
Sanae Tanaka, Bin Wu, Mari Honda, Seiki NANBU, Kazuhisa Suzuki, Keisuke Fukuo, Tsutomu Kazumi   +6 more
openalex   +2 more sources

Which anthropometric measurements including visceral fat, subcutaneous fat, body mass index, and waist circumference could predict the urinary stone composition most? [PDF]

, 2015
Jae Heon Kim, Seung Whan Doo, Kang Su Cho, Won Jae Yang, Yun Seob Song, Jiyoung Hwang, Seong Sook Hong, Soon-Sun Kwon   +7 more
openalex   +1 more source

HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

Advanced Science, EarlyView.
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang, Wenqi Du, Lina Ding, Mengdi Wu, Dongsheng Pei   +4 more
wiley   +1 more source