Results 41 to 50 of about 982,573 (275)

Exercise with food withdrawal at thermoneutrality impacts fuel use, the microbiome, AMPK phosphorylation, muscle fibers, and thyroid hormone levels in rats

Physiological Reports, 2020
Exercise under fasting conditions induces a switch to lipid metabolism, eliciting beneficial metabolic effects. Knowledge of signaling responses underlying metabolic adjustments in such conditions may help to identify therapeutic strategies.
Antonia Giacco, Giuseppe delli Paoli, Roberta Simiele, Marianna Caterino, Margherita Ruoppolo, Wilhelm Bloch, Robert Kraaij, André G. Uitterlinden, Alessandra Santillo, Rosalba Senese, Federica Cioffi, Elena Silvestri, Stefania Iervolino, Assunta Lombardi, Maria Moreno, Fernando Goglia, Antonia Lanni, Pieter deLange   +17 more
doaj   +1 more source

Structural changes in intestinal enteroendocrine cells after ileal interposition in normal rats [PDF]

, 2011
INTRODUCTION: No therapeutic approach has significantly impacted the progression of diabetes. As early improvement of glicaemic control is observed after bariatric surgeries, there is currently a search for surgical procedures that can promote euglycemia
Aparecida Hirata, Bianca Marigliani, Gilmara Aguiar-Yamaguchi, Gustavo Miguel, José-Francisco Borborema, João-Luiz Azevedo, João-Luiz Azevedo, João-Luiz Azevedo, Karina Neves, Linda Bernardes, Lucas Leal, Marcelo Carlini, Maria Alves, Otavio Azevedo, Paolo Lourenco, Rudy Rocha, Wellington Cardia   +16 more
core   +2 more sources

Glucagon-Like Peptide-1 Based Therapies: A New Horizon in Obesity Management [PDF]

Endocrinology and Metabolism
Obesity is a significant risk factor for health issues like type 2 diabetes and cardiovascular disease. It often proves resistant to traditional lifestyle interventions, prompting a need for more precise therapeutic strategies. This has led to a focus on
Jang Won Son, Soo Lim
doaj   +1 more source

MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine. [PDF]

, 2017
The high degree of conservation in microRNA from Caenorhabditiselegans to humans has enabled relatively rapid implementation of findings in model systems to the clinic.
Agarwal, Priyanka, Bhowmick, Neil A, Smith, Bethany   +2 more
core   +1 more source

Optimization of textural properties and formulation of reduced fat Cheddar cheeses containing fat replacers. [PDF]

, 2012
Cheese is becoming one of the most widely utilized food ingredients. Raised awareness of people on healthy lifestyle has led to an increased demand for low-calorie foods, particularly for low and reduced fat cheeses.
Abd. Manap, Mohd. Yazid, Meimandipour, Amir, Mirhosseini, Hamed, Mustafa, Shuhaimi, Nateghi, Leila, Omidizadeh, Alireza, Roohinejad, Shahin, Totosaus, Alfonso   +7 more
core  

ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer [PDF]

, 2017
Low levels of high-density lipoprotein cholesterol (HDLc) have been associated with breast cancer risk, but several epidemiologic studies have reported contradictory results with regard to the relationship between apolipoprotein (apo) A-I and breast ...
Blanco-Vaca, Francisco, Cedó, Lídia, Escolà-Gil, Joan Carles, García-León, Annabel, Lerma, Enrique, López-Vilaró, Laura, Martínez-Cignoni, Melanie Raquel, Santos, David   +7 more
core   +1 more source

LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models

Advanced Functional Materials, EarlyView.
This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran, Diane C.A. Lima, Linda Sandblad, Madeleine Ramstedt, Thereza A. Soares, Stefan Salentinig   +5 more
wiley   +1 more source

Ghrelin [PDF]

, 2015
This work was supported by grants from the NIH (DP2DK105570-01 and 2P30DK046200 to MLA, DK21397 to HJG, K01DK098319 to KMH, K01MH091222 to LH, DK093848 to RJS, R01DK082590 to LS, R01DK097550 to JT, RO1 DK 076037 to MOT, R01DA024680 and R01MH085298 to ...
Abizaid, Adachi, Adeghate, Akashi, Al Massadi, Alvarez-Crespo, Anderson, Andrews, Andrews, Ang, Anker, Armand, Arnold, Arosio, Arvat, Arvat, Asakawa, Asakawa, Ashby, Atalayer, Avau, Bach, Bailey, Baldanzi, Barazzoni, Barim, Barnett, Beiras-Fernandez, Berridge, Berulava, Blake, Blatnik, Blum, Bohdjalian, Bose, Bowers, Bowers, Briggs, Briggs, Broglio, Broglio, Broglio, Broglio, Buscher, Cai, Callahan, Camilleri, Carlini, Carlini, Cecil, Cederberg, Chambers, Chapman, Chen, Chen, Cheng, Chuang, Chuang, Chuang, Cowley, Crum, Cummings, Cummings, Cummings, Cummings, Cummings, Currie, Currow, Damian, Dass, Date, Date, de la Cour, De Smet, De Smet, De Vriese, Deboer, Delhanty, Delhanty, DelParigi, den Hoed, Depoortere, Dezaki, Dezaki, Dezaki, Diano, Dickson, Dickson, Dickson, Dietrich, Dimitriadis, Dina, Dixit, Dornonville de la Cour, Druce, Egido, Engelstoft, Espelund, Falken, Faulconbridge, Faulconbridge, Faulconbridge, Ferrini, Filigheddu, Flanagan, Foster-Schubert, Frayling, Frecka, Fusco, Gagnon, Gagnon, Geliebter, Geliebter, Giordano, Gnanapavan, Goldstein, Goldstone, Granata, Granata, Granata, Granata, Granata, Guan, Guido, Gutierrez, Hady, Hansson, Hardy, Hass, Hataya, Heppner, Heppner, Heppner, Hess, Hewson, Hinney, Holsen, Horvath, Hosoda, Hotta, Hou, Howard, Huda, Inoue, Irako, Iwakura, Iwakura, Janssen, Janssen, Jerlhag, Jerlhag, Jerlhag, Jerlhag, Jerlhag, Jerlhag, Jiang, Kamiji, Kanoski, Kanoski, Karra, Kawahara, Kern, Kirchner, Koch, Kojima, Kojima, Kola, Kola, Korbonits, Korbonits, Korbonits, Korbonits, Kotidis, Koutkia, Kroemer, Kurt, Kwon Jeong, Lage, Lainscak, Lall, Lanfranco, Langer, Lango Allen, Lauria, Lawrence, Lee, Lefkowitz, Lejeune, Lenk, Leung, Levin, Levitzki, Li, Li, Li, Libe, Lim, Lin, Liu, Liu, Longo, Lopez, Lu, Lund, Lutter, Malandrino, Malik, Mani, Mano-Otagiri, Mano-Otagiri, Martins, Martos-Moreno, Masuda, McFarlane, Mericq, Meyer, Miki, Mizutani, Momany, Monteleone, Monteleone, Monteleone, Moon, Muller, Mundinger, Murphy, Murray, Müller, Nagaya, Nagaya, Nagaya, Nagaya, Nakazato, Naleid, Nass, Neary, Nederkoorn, Nishi, Ohgusu, Okumura, Olszewski, Olszewski, Overduin, Palus, Palus, Pantel, Park, Patchett, Peino, Perello, Perez-Tilve, Perez-Tilve, Peterli, Pfluger, Popovic, Porporato, Prudom, Qader, Quarta, Ravussin, Reed, Reimer, Rizza, Rizzo, Romero-Pico, Romero-Pico, Sakata, Sakata, Sakata, Sakata, Sakkou, Salamone, Salehi, Schaeffer, Schellekens, Schmid, Scott, Seoane, Seoane, Sha, Shiiya, Shin, Shin, Shrestha, Shuto, Simonian, Skibicka, Skibicka, Skibicka, Skibicka, Smith, Soriano-Guillen, Speakman, Spencer, Spencer, Stefater, Strassburg, Sun, Sun, Sun, Sun, Szentirmai, Szentirmai, Szentirmai, Szentirmai, Tack, Takaya, Tanofsky-Kraff, Tassone, Theander-Carrillo, Thompson, Timpson, Tolle, Tomasetto, Tong, Tong, Tong, Toshinai, Tschop, Tschop, Tschop, Tsubone, Uchida, Ueberberg, van der Lely, Van der Ploeg, Velasquez, Veldhuis, Verhagen, Verhulst, Vila, Volante, Volante, von Haehling, Walker, Wang, Wardle, Wardle, Weikel, Wellman, Willesen, Williams, Williams, Wortley, Wortley, Wren, Wynne, Yamada, Yang, Yang, Yasuda, Zhang, Zhang, Zhang, Zhao, Zhao, Zigman, Zigman, Zorrilla   +358 more
core   +9 more sources

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Can the inhibition of glycogen synthase kinase 3 mimic the physiological effects of exercise on muscle and other organs?

Advanced Exercise and Health Science
Regular exercise is widely recognized for its numerous health benefits, including enhancing overall well-being, reducing the risk of or alleviating symptoms from various chronic diseases, and slowing the aging process.
Briana L. Hockey, Jessica L. Braun, Rene Vandenboom, Paul J. LeBlanc, Rebecca E.K. MacPherson, Val A. Fajardo   +5 more
doaj   +1 more source