Results 151 to 160 of about 279,890 (362)
Advanced Science, EarlyView.Using a 3D tumor microenvironment (TME)‐on‐a‐chip model, tumor–stromal–immune crosstalk in triple‐negative breast cancer is studied, revealing the TME's combinatorial effect on cancer progression. Integrating single‐cell transcriptomic analysis demonstrates metabolic reprogramming via the kynurenine pathway, highlighting the complex TME cellular ...
Kalpana Ravi +7 more
wiley +1 more source
Advanced Science, EarlyView.Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan +8 more
wiley +1 more source
Microfluidics‐Based Microcarriers for Live‐Cell Delivery
Advanced Science, EarlyView.In this review, recent advancements in microfluidics‐based microcarriers for live‐cell delivery are highlighted. The structural designs of microfluidic‐derived cell‐laden microcarriers are systematically categorized, emphasizing innovative approaches in the fabrication of microspheres, microfibers, and microneedles.
Zhonglin Fang +3 more
wiley +1 more source
Building Solidarity Amid Hostility: Experiences of Fat People in Online Communities [PDF]
arXivOnline communities are important spaces for members of marginalized groups to organize and support one another. To better understand the experiences of fat people -- a group whose marginalization often goes unrecognized -- in online communities, we conducted 12 semi-structured interviews with fat people. Our participants leveraged online communities to
arxiv
Balance between cell survival and death: a minimal quantitative model of tumor necrosis factor alpha cytotoxicity [PDF]
arXiv, 2009 Tumor Necrosis Factor alpha (TNF) initiates a complex series of biochemical events in the cell upon binding to its type R1 receptor (TNF-R1). Recent experimental work has unravelled the molecular regulation of the recruitment of initial signaling complexes that lead either to cell survival or death.
arxiv
EXPERIMENTAL LIVER NECROSIS. V. THE FATS AND LIPOIDS [PDF]
, 1907 Holmes C. Jackson, Richard M. Pearce
openalex +1 more source
Lupus Mastitis Manifesting as Extensive Calcification in the Retromammary Area: A Case Report
Journal of the Korean Society of RadiologyLupus mastitis is a presentation of lupus panniculitis that involves subcutaneous fat in patients with systemic lupus erythematosus (SLE). Moreover, lupus mastitis is a rare condition that typically presents as a palpable breast mass.
Kwang Min Lee +4 more
doaj +1 more source
Advanced Science, EarlyView.A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim +6 more
wiley +1 more source
EXPERIMENTAL FAT NECROSIS: THE ACTION OF PANCREATIC TISSUE UPON SUBCUTANEOUS ADIPOSE TISSUE [PDF]
, 1898 HERBERT U. WILLIAMS
openalex +1 more source
Advanced Science, EarlyView.TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang +8 more
wiley +1 more source