Results 161 to 170 of about 1,603,377 (384)

Targeting Methylglyoxal Metabolism to Enhance Ferroptosis Sensitivity in Tumor Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals how blocking a detox enzyme called GLO1 increases the buildup of a toxic molecule, methylglyoxal (MGO), which triggers cancer cell death by ferroptosis. A protein called PJA1 drives this process. Targeting the PJA1–GLO1 pathway boosts the effectiveness of ferroptosis‐inducing treatments in tumors, offering a promising approach for ...
Xinyue Zhang   +9 more
wiley   +1 more source

Hamartoma Breast, Chondromatous Type. [PDF]

open access: yes, 2011
This case report describes an exceedingly rare case of hamartoma of breast with predominantly chondroid stroma. A 45 year old lady presented with a mobile lump in the upper outer quadrant of left breast, clinically diagnosed as fibroadenoma.
Bhat, V, Jena, M
core  

Rzadki przypadek obumierania podskórnej tkanki tłuszczowej u noworodków

open access: yesPrzegląd Dermatologiczny, 2011
Introduction. Subcutaneous fat necrosis of the newborn (SCFN) isa rare disorder of the subcutaneous adipose tissue. Subcutaneous fat necrosis of the newborn usually appears days to weeks after a complicatedperinatal period and the most frequent risk ...
Jadwiga Roszkiewicz   +4 more
doaj  

A Case of Subcutaneous Fat Necrosis of the Newborn [PDF]

open access: hybrid, 1996
So Yun Choi   +3 more
openalex   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

Humphrey Center News: Spring 1991 v. 6, no. 1 [PDF]

open access: yes, 1991
Newsletter of the Hubert H.
Anthony, Richard P.   +1 more
core  

Resident Macrophage‐Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor‐Associated Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma   +11 more
wiley   +1 more source

Membranous fat necrosis of gall bladder, a case report and literature review. [PDF]

open access: yesInt J Surg Case Rep, 2023
Salehi M   +5 more
europepmc   +1 more source

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