Results 171 to 180 of about 1,603,377 (384)
Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow
Advanced Science, EarlyView.DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley +1 more source
Pericardial Lipoma With Fat Necrosis. [PDF]
JACC Case Rep, 2022 Higashimoto N +4 more
europepmc +1 more source
ACUTE PANCREATITIS WITH VERY EXTENSIVE FAT NECROSIS
, 1912 Lucius W. Hotchkiss
openalex +2 more sources
Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor α in rats [PDF]
, 2000 Tohru Utsunomiya +3 more
openalex +1 more source
Restoring NK Cell Cytotoxicity Post‐Cryopreservation via Synthetic Cells
Advanced Science, EarlyView.In this study, it is shown that 1‐day co‐culture with activated T cells or IL‐2‐presenting synthetic cells significantly enhances NK cell motility and cytotoxicity in 2D and 3D. Notably, synthetic cells restore the impaired cytotoxic function of cryopreserved NK and CAR‐NK cells in 3D.
Xiangda Zhou +20 more
wiley +1 more source
Epipericardial fat necrosis: a case report of an underdiagnosed disease. [PDF]
Porto Biomed J, 2023 Matos ML +5 more
europepmc +1 more source
Advanced Science, EarlyView.In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source
Ectopic epipericardial fat necrosis: a case report
Surgical Case ReportsBackground Epipericardial fat necrosis (EFN) is a rare disease in which local inflammation and necrosis occur in the adipose tissue surrounding the heart, particularly epicardial fat.
Ryusei Yoshino +6 more
doaj +1 more source
Advanced Science, EarlyView.In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou +17 more
wiley +1 more source