Results 191 to 200 of about 312,153 (299)

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis. [PDF]

Medicina (Kaunas), 2022
Zivadinovic JD, Stojanovic MM, Stosic MD, Zivadinovic AR, Jankovic R, Gmijovic MD, Golubovic I, Stosic B, Ignjatovic NS, Stojanovic MP.   +9 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Fat necrosis: A neglected side effect of intramuscular injections. [PDF]

Clin Case Rep, 2022
Chaima K, Mariem A, Emna B, Slim C, Fatma H, Tahya B, Hamida T.   +6 more
europepmc   +1 more source

Pictorial essay of fat necrosis [PDF]

, 2000
A. A. Murphy, JR Smales
openalex   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Forgotten Surgical Sponge Mimicking Fat Necrosis Following Breast Reduction Surgery. [PDF]

Plast Reconstr Surg Glob Open
Scharfetter S, Weitgasser L, Wimmer F, Ebner B, Russe E, Wechselberger G.   +5 more
europepmc   +1 more source

Inside Out: Bone Marrow Necrosis and Fat Embolism Complicating Sickle-β+ Thalassemia [PDF]

, 2016
Jori E. May, Joseph C. Sullivan, Daniel Lavie, Katherine LaVie, Marisa B. Marques   +4 more
openalex   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Radiologic Evaluation of Subcutaneous Fat Necrosis Complicated by an Abscess in a Newborn: A Case Report. [PDF]

Cureus
Al-Kharabsheh YE, Isufi E, Brown J, Gadaga C, Ghouri M.   +4 more
europepmc   +1 more source