Results 201 to 210 of about 1,419,683 (340)

PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan   +17 more
wiley   +1 more source

Encapsulated Fat Necrosis after Lipolysis of the Calf with Phosphatidylcholine [PDF]

open access: bronze, 2008
Falk G. Bechara   +5 more
openalex   +1 more source

Fat Necrosis of the Breast [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1931
openaire   +3 more sources

Epigenetic Regulation of DAPK1 and Netrin‐1 Drives Diabetic Encephalopathy

open access: yesAdvanced Science, EarlyView.
This study identifies a microRNA (miR)‐216a‐5p/death‐associated protein kinase 1 (DAPK1)/hepatocyte nuclear factor 1 homeobox A (HNF1A)/Netrin‐1 signaling axis in diabetic encephalopathy (DE). In leptin receptor‐deficient (db/db) and streptozotocin (STZ)‐induced diabetic mice, reduced miR‐216a‐5p increases DAPK1 expression, disrupting HNF1A binding to ...
Yang Zhou   +13 more
wiley   +1 more source

Tumor Necrosis Factor-α Gene -308 G/A Polymorphism Modulates the Relationship between Dietary Fat Intake, Serum Lipids, and Obesity Risk in Black South African Women [PDF]

open access: bronze, 2010
Yael Joffe   +7 more
openalex   +1 more source

Tunneling Nanotube‐Mediated Transcellular Autophagy Alleviates Cadmium Induced Hepatocyte Injury

open access: yesAdvanced Science, EarlyView.
ROS accumulation is an important upstream signal for activating transcellular autophagy. Incomplete autophagy and TNT formation are necessary conditions for activating transcellular autophagy, and the disruption of the autophagic fusion mechanism is a trigger for activating transcellular autophagy.
Tao Wang   +13 more
wiley   +1 more source

Association of Severe Insulin Resistance With Both Loss of Limb Fat and Elevated Serum Tumor Necrosis Factor Receptor Levels in HIV Lipodystrophy

open access: bronze, 2000
Dennis C. Mynarcik   +4 more
openalex   +1 more source

Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
As an inevitable disease, muscle atrophy has received more attention. Because the factors that induce this disease are diverse, achieving a complete cure is still impossible. Wearable bioelectronics provides a more comfortable, low‐cost, and efficient way of home care for the monitoring and treatment of muscle atrophy. Therefore, this review summarizes
Shuai Zhang   +4 more
wiley   +1 more source

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