Results 241 to 250 of about 1,419,683 (340)
Reply: Perforator Number Does Not Predict Fat Necrosis
Pierre M. Chevray
openalex +1 more source
Severe hypercalcaemia due to subcutaneous fat necrosis: presentation, management and complications
Daniel E Shumer+3 more
semanticscholar +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen+6 more
wiley +1 more source
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu+7 more
wiley +1 more source
Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez+20 more
wiley +1 more source
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma+11 more
wiley +1 more source
Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu+14 more
wiley +1 more source
Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart+4 more
wiley +1 more source