Results 31 to 40 of about 1,440,768 (240)

A closed manifold is a fat CW complex [PDF]

open access: yesarXiv, 2023
The main purpose of this paper is to introduce a new smooth version of a CW complex named a fat CW complex, and to show that it includes all closed manifolds, because existing smooth versions of CW complexes (e.g. [Iwa22]) do not have such property.
arxiv  

Flexible water excitation for fat-free MRI at 3 Tesla using lipid insensitive binomial off-resonant RF excitation (LIBRE) pulses [PDF]

open access: yesMRM 79 2018 3007-3017, 2019
Purpose: To develop a robust and flexible low power water excitation pulse that enables effective fat suppression at high magnetic field strength. Methods: A water excitation method that uses spatially non-selective pulses was optimized in numerical simulations, and implemented and tested in phantoms and healthy volunteers at 3T.
arxiv   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

The regularity index, Hilbert function of fat points and the embedding [PDF]

open access: yesarXiv, 2023
Let $m \ge n$, $\phi_{n,m}: \mathbb P^n \to \mathbb P^m$, $\phi_{n,m}(a_1, \ldots, a_n)=(a_1, \ldots, a_n, 0, \ldots, 0)$, be the embedding, $Z=m_1P_1+\cdots+m_sP_s$ be fat points in $\mathbb P^n$ and $\phi_{n,m}(Z)=m_1\phi_{n,m}(P_1)+\cdots+m_s\phi_{n,m}(P_s)$ be fat points in $\mathbb P^m$.
arxiv  

Histopathological changes in the pancreas of cattle with abdominal fat necrosis

open access: yesJournal of Veterinary Medical Science, 2016
The association between pancreatic disorder and abdominal fat necrosis in cattle remains unclear. The pancreases of 29 slaughtered cattle with or without fat necrosis were collected to investigate pathological changes.
C. Tani   +7 more
semanticscholar   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 622-633, April 2025.
We explored the role of FSH on the synovium and found that FSH was able to mediate the development of osteoarthritis by acting on the FSH receptor (FSHR) to promote the production and release of inflammatory factors through the activation of the NFκB signaling pathway. Previous studies have suggested that women with higher follicle‐stimulating hormone (
Yu Chen   +6 more
wiley   +1 more source

Rate-Equation Modelling and Ensemble Approach to Extraction of Parameters for Viral Infection-Induced Cell Apoptosis and Necrosis [PDF]

open access: yesJ. Chem. Phys. 145 (9), Article 094103, 8 pages (2016), 2016
We develop a theoretical approach that uses physiochemical kinetics modelling to describe cell population dynamics upon progression of viral infection in cell culture, which results in cell apoptosis (programmed cell death) and necrosis (direct cell death).
arxiv   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, Volume 15, Issue 5, Page 836-855, May 2025.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

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