Results 251 to 260 of about 365,594 (306)

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Relation between the Epicardial Fat Thickness and the Cardiac Conduction System in Children and Adolescents with Diabetes.

Horm Res Paediatr
Raafat S, Ahmed R, Mowafi I, Adel H.
europepmc   +1 more source

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Determination of Deltoid Fat Pad Thickness

JAMA, 1997
Objective. —To measure deltoid fat pad thickness and determine the optimal needle length for deltoid intramuscular immunization in healthy adults. Design, Setting, and Participants. —Prospective study of 220 healthy health care workers (126 women, 94 men) at the Mayo Medical Center, Rochester, Minn. Main Outcome Measures.
Gregory A Poland
openaire   +3 more sources

Association of carotid intima-media thickness with mesenteric, preperitoneal and subcutaneous fat thickness

Atherosclerosis, 2005
Carotid intima-media thickness (IMT) is an established surrogate marker for atherosclerosis. We have previously reported that abdominal fat, notably mesenteric fat, was a major explanatory variable for multiple cardiovascular risk factors. Given the intimate relationships between visceral fat, cardiovascular risk factors and atherosclerosis, we ...
K H, Liu, Y L, Chan, J C N, Chan, W B, Chan   +3 more
openaire   +4 more sources

Epicardial fat thickness in infants of diabetic mothers

Journal of Neonatal-Perinatal Medicine, 2021
BACKGROUND: Epicardial fat thickness (EFT) in adults and children has been related to the metabolic syndrome and other cardiovascular risk factors; however, scarce studies have evaluated it in infants of diabetic mothers (IDM) in whom, alterations in the thickness of the interventricular septum have been reported.
M M, Vela-Huerta, N, Amador-Licona, R, Domínguez-Damián, A, Heredia-Ruiz, H V, Orozco-Villagomez, J M, Guízar-Mendoza, S, Alarcon-Santos   +6 more
openaire   +2 more sources

Relation of Echocardiographic Epicardial Fat Thickness and Myocardial Fat

The American Journal of Cardiology, 2010
Epicardial and myocardial fats increase with degree of visceral adiposity and possibly contribute to obesity-associated cardiac changes. Echocardiographic epicardial fat thickness is a new and independent marker of visceral adiposity. The aim of this study was to test whether echocardiographic epicardial fat is related to myocardial fat.
A.E. Malavazos, G. Di Leo, F. Secchi, E. N. Lupo, G. Dogliotti, C. Coman, L. Morricone, M.M. Corsi Romanelli, F. Sardanelli, G. Iacobellis   +9 more
openaire   +3 more sources

Epicardial Fat Thickness and Primary Aldosteronism

Hormone and Metabolic Research, 2016
Primary aldosteronism (PA) is associated with increased cardiovascular risk and left ventricle (LV) changes. Given its peculiar biomolecular and anatomic properties, excessive epicardial fat, the heart-specific visceral fat depot, can affect LV morphology.
Iacobellis, G., PETRAMALA, LUIGI, MARINELLI, CRISTIANO, CALVIERI, CAMILLA, ZINNAMOSCA, LAURA, CONCISTRE, ANTONIO, IANNUCCI, Gino, DE TOMA, Giorgio, LETIZIA, Claudio   +8 more
openaire   +2 more sources

CT Evaluation of Normal Interatrial Fat Thickness

Journal of Computer Assisted Tomography, 1996
This study was performed to determine the normal thickness of fat in the interatrial septum as demonstrated by CT.Eighty-seven subjects underwent helical chest CT examination as part of a separate protocol to compare the quantification of coronary artery calcification by CT to coronary angiographic findings, using a slice width of 3 mm, reconstructed ...
L S, Broderick, D J, Conces, R D, Tarver
openaire   +2 more sources