Results 31 to 40 of about 669,025 (322)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Transformações no Envolvimento Paterno ao Longo dos Seis Primeiros Meses do Bebê na Creche

Psicologia: Teoria e Pesquisa
Resumo Este trabalho investigou o envolvimento de pais com seus bebês e com a creche nos seis primeiros meses de frequência do bebê no berçário. Por meio de um estudo de caso coletivo de caráter longitudinal, quatro pais responderam a entrevistas em três
Marília Reginato Gabriel, Rita de Cássia Sobreira Lopes   +1 more
doaj   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Implikasi Hubungan Perdata Anak Luar Perkawinan Dengan Laki-laki Sebagai Ayahnya [PDF]

, 2016
Based on the Constitutional Court Number 46 /PUU-VII / 2010, the civil relationship between childwith his father and his father's family based on theirblood relationship between the child and his fatherand mother, although the both do not have ...
Masykuroh, Y. W. (Yufi)
core  

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

The Insistence of Blackness and the Persistence of Antiblackness in Ireland

Australian Journal of Social Issues, EarlyView.
ABSTRACT This paper positions Ireland as a critical site for examining the insistence of blackness and an antiblackness created and sustained through Irish ethnonationalist imaginaries and exclusionary processes. Drawing on connected sociologies and Irish Black Studies, this enquiry argues that antiblackness in Ireland operates as a generational force,
Philomena Mullen
wiley   +1 more source

ASSESSING COMMON GENETIC AND ENVIRONMENTAL EFFECTS ON THE ASSOCIATION BETWEEN PARENT-CHILD RELATIONS AND INTIMATE PARTNER RELATIONSHIP QUALITY

Хабаршы. Заң сериясы, 2020
The current study examined the genetic and environmental architecture of early life parent-child relations and intimate partner relationship quality later in life.
Kevin M. Beaver, Eric J. Connolly, Meghan W. Rowland   +2 more
doaj   +1 more source

The Peculiarities of Parent-Child Relationship among Teenagers who are Addicted to Online Games

Психолого-педагогические исследования, 2021
The family is one of the main institutions for raising a child, starting from the moment of birth and ending with his formation of a mature personality. The development of parent-child relations will determine the further formation of a person, including
Eliseeva M.I., Krieger E.E.
doaj   +1 more source

Law\u27s Constitution: A Relational Critique [PDF]

, 2002
It is a simple fact: we begin from others. Without others we, quite literally, could not live, feel, be born. Every mother, every mother\u27s partner, every father, every child, knows this.
Nourse, Victoria
core   +1 more source

Understanding Youth Assaults of Police Officers in Australia: A Power Threat Meaning Framework Analysis

Australian Journal of Social Issues, EarlyView.
ABSTRACT This study explores youth violence towards police officers in Australia through the Power Threat Meaning Framework (PTMF) to better understand the underlying factors contributing to such violence; focusing on power dynamics, childhood adversity, and trauma.
Dimitra Lattas, Kelly Hine, Catherine Creamer, Kelley Burton, Katelyn Davenport‐Klunder   +4 more
wiley   +1 more source