Results 21 to 30 of about 56,955 (278)

New Discoveries, Concepts and Questions in the Search to Understand Fathers' Influence on Child Development

open access: yesСовременная зарубежная психология, 2022
Just 20 years ago scholars called the sphere of fatherhood research “understudied.” Today the view is quite different. Fatherhood studies have multiplied in universities across the world, and new discoveries have revealed opportunities for ...
B.A. Hoffman
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

THE EDUCATIONAL POTENTIAL OF FATHERHOOD: CONCEPTUAL BASES OF RESEARCH AND SUPPORT

open access: yesОбразование и наука, 2017
Introduction. Nowadays, under the conditions of a general crisis of family relations, fatherhood as a social phenomenon and institution increasingly attracts the interest of researchers in various fields of humanitarian knowledge.
V. I. Zagvyazinsky, A. D. Chekhonin
doaj   +1 more source

Elimination of the Category of Masculinity and Fatherhood in the Theory and Practice of Education

open access: yesPaedagogia Christiana, 2012
One of the most important sources of the modern crisis of education is the absence of the category of fatherhood – the foundations of that crisis lie in the field of philosophy, culture and civilization.
Witold Starnawski
doaj   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

open access: yesAdvanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen   +12 more
wiley   +1 more source

Egalitarian Fatherhood – a Present and Engaged Father

open access: yesHoryzonty Wychowania
RESEARCH OBJECTIVE: The purpose of this article is to provide a scholarly reflection on egalitarian (partnership-based) fatherhood and the factors that condition and constitute it.
Anna Błasiak, Martyna Żurek
doaj   +1 more source

LONGITUDE STUDY OF CONSTRUCTIVE FATHERHOOD STRATEGIES DEVELOPMENT

open access: yesВестник Кемеровского государственного университета, 2017
The article represents the definition, characteristics and theoretical approaches and psychological basis to constructive fatherhood strategies development.
Yu. V. Borisenko
doaj   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

open access: yesAdvanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang   +9 more
wiley   +1 more source

Making Fathers Count: Assessing the Progress of Responsible Fatherhood Efforts [PDF]

open access: yes, 2002
This report provides a history of the issue of fatherhood in policy debates and philanthropic action from the late 1960's through the present day. It then outlines research findings in seven core areas of fatherhood and discusses accomplishments and ...
Kathleen Reich, Kathleen Sylvester
core  

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