Network Localization of Fatigue in Multiple Sclerosis
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Local and non-local normalised equivalent strain functionals for cyclic fatigue [PDF]
The concept of Cyclic Normalised Equivalent Strain Functionals (CNESnFs) suitable for lowcyclic fatigue is developed in this paper. It reduces any fatigue strength and durability model to a unique form what facilitates the models comparison ...
Mikhailov, SE, Namestnikova, IV
core +1 more source
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study [PDF]
<p>Background: Fatigue is a major component of living with ankylosing spondylitis (AS), though it has been largely over-looked, and currently there are no specific agreed management strategies.</p> <p>Methods: This qualitative ...
A Calin +38 more
core +2 more sources
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Fatigue analysis of catenary contact wires for high speed trains [PDF]
The fatigue fracture is one of the most critical failures which may occur on the high speed network because it is undetectable and it has a huge impact on traffic disruption.
BALMES, Etienne +3 more
core
Low cycle fatigue life improvement of AISI 304 by initial and intermittent wire brush hammering [PDF]
The effects of hammering by wire brush as a method of improving low cycle fatigue life of highly ductile austenitic stainless steel AISI 304 have been investigated through an experimental study combining imposed strain fatigue tests and assessment of ...
BRAHAM, Chedly +4 more
core +3 more sources
Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund +3 more
wiley +1 more source
Teaching durability in automotive applications using a reliability approach [PDF]
Fatigue phenomena, which appear generally below the yield stress, is the cause of more than 80 % of in-service mechanical failures. However, the optimization of the weight and cost when designing mechanical components or structures, linked to improved ...
BIGNONNET, André +3 more
core +5 more sources
Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung +190 more
wiley +1 more source

