Results 41 to 50 of about 970,221 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Comparison of S-N Curves from International Fatigue Design Standards for a Better Understanding of the Long-Term Operation of Offshore Wind Turbine Welded Foundations

Wind
Fatigue poses significant challenges for the structural integrity of monopiles, the most common type of foundation for offshore wind turbines. These structures are usually manufactured by rolling and welding together large steel plates.
Federico Della Santa, Gianluca Zorzi, Ali Mehmanparast   +2 more
doaj   +1 more source

Fatigue test bench manufacturing by reusing a parallel lathe [PDF]

, 2018
Fatigue life of machined parts strongly depends on their surface condition. The rotating bar bending fatigue testing method is widely used to obtain the fatigue behavior of metallic materials due to its simplicity.
Bermudo Gamboa, Carolina, Martín Béjar, Sergio, Sevilla-Hurtado, Lorenzo, Trujillo Vilches, Francisco Javier   +3 more
core  

Application of the linear matching method to creep-fatigue failure analysis of cruciform weldment manufactured of the austenitic steel AISI type 316N(L) [PDF]

, 2012
This paper demonstrates the recent extension of the Linear Matching Method (LMM) to include cyclic creep assessment [1] in application to a creep-fatigue analysis of a cruciform weldment made of the stainless steel AISI type 316N(L). The obtained results
Chen H. F., H. Chen, Y. Gorash
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Correlation among Energy Based Fatigue Curves and Fatigue Design Approaches

Procedia Structural Integrity, 2018
Abstract In this paper, with reference to the strain controlled fatigue characterization of AISI 304L stainless steel, the correlations between plain material fatigue curves based on different definitions of the strain energy densities, namely the elastic, plastic and elastoplastic strain energy densities evaluated under the cyclic stress-strain ...
B. Atzori, M. Ricotta, G. Meneghetti
openaire   +3 more sources

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source

Fatigue Reliability and Calibration of Fatigue Design Factors for Offshore Wind Turbines

Energies, 2012
Consequences of failure of offshore wind turbines (OWTs) is in general lower than consequences of failure of, e.g., oil & gas platforms. It is reasonable that lower fatigue design factors can be applied for fatigue design of OWTs when compared to ...
Sergio Márquez-Domínguez, John D. Sørensen   +1 more
doaj   +1 more source