Results 61 to 70 of about 970,221 (310)

EVAPRED - A CODE FOR FATIGUE ANALYSIS OPTIMIZATION [PDF]

INCAS Bulletin, 2010
The fatigue can be, in fact, defined as: “failure under a repeated or otherwise varying load, which never reaches a level sufficient to cause failure in a single application”.Physical testing is clearly unrealistic for every design component.
Dorin LOZICI-BRÎNZEI
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Paired Comparisons-based Interactive Differential Evolution [PDF]

, 2009
We propose Interactive Differential Evolution (IDE) based on paired comparisons for reducing user fatigue and evaluate its convergence speed in comparison with Interactive Genetic Algorithms (IGA) and tournament IGA.
Pallez, Denis, Takagi, Hideyuki
core   +3 more sources

Fatigue of intermittently stimulated quadriceps during imposed cyclical lower leg movements [PDF]

, 1992
During prolonged experiments the influence of knee angular velocity, and stimulation parameters (interpulse interval (IPI), duty cycle (DC), number of pulses per cycle (NP)) on fatigue-induced torque\ud decline of paralyzed human quadriceps was studied ...
Boom, H.B.K., Fidder, Marc, Franken, H.M., Franken, Henry M., Veltink, Petrus H.   +4 more
core   +4 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Determination of the Statistical Power of Fatigue Characteristics in Relation to the Number of Samples

Applied Sciences
The paper presents guidelines included in the ISO 12107:2003 standard regarding the number of samples for determining the fatigue characteristics in the high cycle range. The proposed normative values were compared with the classical statistical approach.
Przemysław Strzelecki, Janusz Sempruch
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Comparative Study of Local Stress Approaches for Fatigue Strength Assessment of Longitudinal Web Connections

Journal of Marine Science and Engineering
Ship structures are subjected to cyclic loading from waves and currents during operation, which can lead to fatigue failure, particularly at locations with structural discontinuities such as welds.
Ji Hoon Kim, Jae Sung Lee, Myung Hyun Kim   +2 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Fatigue Design Evaluation of Railway Bogie with Full-Scale Fatigue Test

Advances in Materials Science and Engineering, 2017
The bogie frame of a railway is an important structural member for the support of vehicle loading. In general, more than 25 years’ durability is necessary.
Jung-Won Seo, Hyun-Moo Hur, Hyun-Kyu Jun, Seok-Jin Kwon, Dong-Hyeong Lee   +4 more
doaj   +1 more source