Results 221 to 230 of about 37,853 (293)

An examination of core beliefs in generalized anxiety disorder

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Objective Generalised anxiety disorder (GAD) is characterised by uncontrollable worries. Cognitive behaviour therapy (CBT) is an effective treatment for GAD; however, manualised treatments rarely include interventions to target core beliefs. This study aimed to (1) explore the core beliefs about the self that are endorsed by individuals with ...
Amy E. Doust   +4 more
wiley   +1 more source

Childhood emotion reactivity and regulation as predictors of sleep quality: A longitudinal study

open access: yesBritish Journal of Developmental Psychology, EarlyView.
Abstract This longitudinal study examined the predictive role of emotion reactivity and regulation on sleep quality across early to middle childhood. Participants were typically developing Swedish children (N = 116, 49% girls), with reactivity and regulation assessed at ages 3, 6 and 9 years, and sleep quality measured at the age of 9 years.
Emma J. Heeman   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos   +16 more
wiley   +1 more source

Circulating Rhythmic Metabolites and Causal Risk of Type 2 Diabetes in Adults in the Canadian Longitudinal Study on Aging

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Circadian regulation of metabolism is an important factor in metabolic health, yet the role of rhythmic metabolites in Type 2 diabetes development remains poorly understood. This study investigated associations between circulating rhythmic metabolites and incident Type 2 diabetes risk and evaluated causal relationships using two‐sample ...
Divya Joshi   +10 more
wiley   +1 more source

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