Results 71 to 80 of about 509,711 (305)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Effects of upper-stress limit and stress range on fatigue performance of a novel thermoplastic glass fiber reinforced polypropylene bar: Experimental investigation and fatigue life model

Case Studies in Construction Materials
Thermoplastic glass fiber reinforced polypropylene (GFRPP) bars, compared with traditional thermosetting GFRP bars, demonstrate superior advantages including post-forming thermal processability and recyclability.
Haoyu Liu, Anni Wang, Qun Chen, Xiaogang Liu   +3 more
doaj   +1 more source

A new stress field intensity model and its application in component high cycle fatigue research.

PLoS ONE, 2020
Fatigue limit load is one of the most important and concerned factors in designing and manufacturing critical mechanical parts such as the crankshafts.
SongSong Sun
doaj   +1 more source

Fatigue as a limitation to performance [PDF]

Experimental Physiology, 2021
Derek Ball, Ronald J. Maughan
openaire   +2 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Rapid evaluation of fatigue limit using infrared thermography: comparison between two methods for quantifying temperature evolution

Mechanical Engineering Journal, 2017
The technique of rapid evaluation of fatigue limit using infrared thermography was developed and has been paid attention during the past 30 years. This technique is beneficial because it also makes possible to detect the location of fatigue damage in ...
Ryogo KAWAI, Takumi YOSHIKAWA, Yu KUROKAWA, Yousuke IRIE, Hirotsugu INOUE   +4 more
doaj   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

A differential CDM model for fatigue of unidirectional metal matrix composites [PDF]

A multiaxial, isothermal, continuum damage mechanics (CDM) model for fatigue of a unidirectional metal matrix composite volume element is presented. The model is phenomenological, stress based, and assumes a single scalar internal damage variable, the ...
Arnold, S. M., Kruch, S.
core   +1 more source

Development and implementation of the Abaqus subroutines and plug-in for routine structural integrity assessment using the linear matching method [PDF]

, 2012
In recent years the Linear Matching Method (LMM) has been developed as a tool for structural integrity assessments of components subjected to cyclic loading conditions.
Chen, Haofeng, Tipping, David, Ure, James Michael   +2 more
core