Results 51 to 60 of about 7,418,430 (299)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

MODELLING OF STRESS GRADIENT EFFECT ON FATIGUE LIFE USING WEIBULL BASED DISTRIBUTION FUNCTION [PDF]

open access: yes, 2013
In the present paper, a new approach is developed in order to take into account the stress gradient effect on fatigue life of structural components. The proposed approach is based on the weakest link concept in which the shape coefficient of the Weibull ...
PALIN-LUC, Thierry   +2 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis and Experimental Study for Fatigue Performance of Wing-Fuselage Connection Structure for Unmanned Aerial Vehicle

open access: yesAerospace
(1) Background: As the principal structural element of an unmanned aerial vehicle (UAV), a lightweight, high-performance wing-fuselage connection structure plays an important role in UAV structural integrity.
Lijun Sui, Youchao Sun, Min Kang
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Experimental Study on Fatigue Properties of Q420 Bridge Steel in a Deicing Salt Corrosion Environment in Western China

open access: yesBuildings
The corrosive environment in the western region will adversely affect the fatigue performance of bridges. In order to determine the influence of the corrosion environment in western China on the fatigue failure of bridges, this paper simulated corrosion ...
Tingkun Zhou   +5 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

The Effect of microstructural heterogeneities on the fatigue behaviour of 22MnB5 sheet steel [PDF]

open access: yes, 2013
This work deals with the effect of heat treatment on the fatigue strength of a rear axial beam and aims to propose a methodology suitable and reliable for fatigue design.
PESSARD, Etienne   +4 more
core  

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