Results 81 to 90 of about 573,041 (359)

Solvent extraction of jojoba oil from pre-pressed jojoba meal

open access: yesGrasas y Aceites, 2004
The solvent extraction process of jojoba oil from the meal cake obtained after the mechanical pressing of jojoba seeds was studied. Commercial hexane and petroleum ether were used as solvents and the extraction was carried out at temperatures ranging ...
Ferial A. Zaher   +2 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Practical Risk Assessment and Management Issues Arising were we to Adopt Low-Dose Linearity for all Endpoints

open access: yesDose-Response, 2011
The 2009 National Research Council report, Science and Decisions , proposes harmonizing dose-response approaches for cancer and non-cancer endpoints, and for non-cancer quantitative risk assessment, this would usually take the form of a low-dose linear ...
Lorenz R. Rhomberg Ph.D., FATS
doaj   +1 more source

Trans unsaturated fatty acids : a study of methodology and levels in New Zealand food fats including milkfat : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Biochemistry at Massey University, New Zealand [PDF]

open access: yes, 1997
Trans fatty acids (TFAs) occur naturally in small amounts in foods such as milk, butter and tallow as a result of biohydrogenation by ruminant gut microflora. They are formed in much larger quantities during chemical hydrogenation of fats and oils.
Fong, Bertram Ian Yin
core  

Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs [PDF]

open access: yes, 2012
BACKGROUND: Fibroblast growth factor 21 (FGF21), whose expression is induced by peroxisome proliferator-activated receptor alpha (PPARalpha), has been recently identified as a novel metabolic regulator which plays a crucial role in glucose homeostasis ...
Eder, Klaus   +2 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Pretreatment of cottonseed flakes with proteases and an amylase for higher oil yields

open access: yesGrasas y Aceites, 2007
The effect of enzymatic pretreatment of cottonseed flakes on oil extractability was studied. The enzymes investigated included bacterial protease (Bp), papain (Pa), savinase (S), termamyl (T), pectinase (Pe) and cellulase (C).
Fakhriya S. Taha, Minar M. Hassanein
doaj   +1 more source

Acute effects of elevated NEFA on vascular function: a comparison of SFA and MUFA [PDF]

open access: yes, 2010
There is emerging evidence to show that high levels of NEFA contribute to endothelial dysfunction and impaired insulin sensitivity. However, the impact of NEFA composition remains unclear.
Abby K. Thompson   +9 more
core   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

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