Results 171 to 180 of about 1,126,784 (352)

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

Flippase‐Mediated Hybrid Vesicle Division

Advanced Materials, EarlyView.
The successful reconstitution of Drs2p–Cdc50p flippase in small and giant polymer lipid hybrid vesicles is illustrated. The hybrid vesicles show adenosine 5′‐triphosphate consumption and flipping of 2‐dioleoyl‐sn‐glycero‐3‐phospho‐l‐serine lipids from the inner to the outer leaflet.
Paula De Dios Andres, Amalie Benfeldt Purup, Grégory Beaune, Jaakko V. I. Timonen, Joseph A. Lyons, Brigitte Städler   +5 more
wiley   +1 more source

Multiomics analysis revealed the regulatory role of chenodeoxycholic acid in fatty acid metabolism and lipid homeostasis. [PDF]

Lipids Health Dis
Li L, Ren X, Gao X, Zhao Y, Ma Y, Gong J, Yang S, Sun Y, Wang Y.   +8 more
europepmc   +1 more source

Regulation of the Metabolism of Rabbit Liver Mitochondria by Long Chain Fatty Acids and Other Uncouplers of Oxidative Phosphorylation

, 1969
E.Jack Davis, D. M. Gibson
openalex   +1 more source

Metabolism of red-cell lipids I. Incorporation in vitro of fatty acids into phospholipids from mature erythrocytes [PDF]

, 1965
E. Mulder, L.L.M. Van Deenen
openalex   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Tissue-Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency. [PDF]

Proteomics
Khumalo SG, Lindeque JZ, Venter M.
europepmc   +1 more source

The formation and metabolism of phenyl-substituted fatty acids in the ruminant [PDF]

, 1964
TW Scott, PFV Ward, RMC Dawson
openalex   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Identification of Fatty Acid Metabolism Disorder-Related Gene Signature in Septic Cardiomyopathy. [PDF]

J Inflamm Res
Li L, Zhang T, Yang C, Meng Q, Wang S, Fu Y.   +5 more
europepmc   +1 more source