Results 181 to 190 of about 806,764 (304)

METABOLISM OF ESSENTIAL FATTY ACIDS

Journal of Biological Chemistry, 1957
David R. Howton, James F. Mead
openaire   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

A prognostic model correlated with fatty acid metabolism in Ewing's sarcoma based on bioinformatics analysis. [PDF]

Open Med (Wars)
Chen X, Yang Y, Li D, Ye E, He B, Yu M, Luo J, Zhang J.   +7 more
europepmc   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Hyperinflammation by Human Macrophages Induced by SARS-CoV-2 Anti-Spike IgG Is Dependent on Glucose and Fatty Acid Metabolism. [PDF]

Eur J Immunol
Geyer CE, Almeida L, Mes L, Otto F, Mak WA, Heieis GA, Veth J, de Taeye SW, Caniels TG, Bijl TPL, van Gils MJ, de Winther M, Amsterdam UMC COVID‐19 Biobank, Van den Bossche J, Chen HJ, Houtkooper RH, Everts B, den Dunnen J.   +17 more
europepmc   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

A distinctive human fatty acid metabolism profile associated with osteoporotic patients. [PDF]

Sci Rep
Hu X, Lin R, Yan J, Wang D, Liu Y, Fu D, Huang Y.   +6 more
europepmc   +1 more source

Polyunsaturated Fatty Acid Metabolism during Lactation [PDF]

, 2000
Demmelmair, Hans, Sauerwald, Thorsten, Fidler, N., Baumheuer, M., Koletzko, Berthold   +4 more
openaire   +3 more sources

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

hnRNP A1 inhibits colorectal cancer tumorigenesis and progression by regulating fatty acid metabolism and RNA stability. [PDF]

Cell Death Discov
Ji K, Zhou L, Zhang T, Fan H, Xie G, Man W, Wang C, Tian Y, Chen L, Wang G, Liu M, Zhu B, Zhang W, Yu G.   +13 more
europepmc   +1 more source