Results 181 to 190 of about 1,111,197 (376)

Synthesis of Rhodamine TEMPO Conjugates via Isonitrile‐Based Multicomponent‐Reactions for Mitochondria‐Targeted ROS‐Detection in Cancer Cells

open access: yesAdvanced Sensor Research, EarlyView.
This article explores the development of rhodamine TEMPO conjugates via the Ugi‐multicomponent reaction to detect reactive oxygen species (ROS) in living cells. The sensors are highly selective for mitochondria in both cancer and normal cell lines, with fluorescence quenching and EPR spectroscopy offering precise ROS detection.
Haider N. Sultani   +6 more
wiley   +1 more source

Antibiotic–Polycationic Peptide Conjugation as an Effective Strategy to Overcome Daptomycin Resistance

open access: yesAdvanced Therapeutics, EarlyView.
Antimicrobial resistance necessitates the development of new antibiotics with “resistance‐breaking” properties. In this study, conjugation of polycationic peptides is proven to represent a versatile strategy for the fast and affordable reactivation of daptomycin.
Sari Rasheed   +21 more
wiley   +1 more source

Metabolism of Essential Fatty Acids

open access: hybrid, 1960
Armand J. Fulco, James F. Mead
openalex   +2 more sources

Alternate pathways of metabolism of short-chain fatty acids [PDF]

open access: bronze, 1968
Warner S. Wegener   +3 more
openalex   +1 more source

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi   +18 more
wiley   +1 more source

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