Results 221 to 230 of about 1,111,197 (376)

SGLT2 inhibitor upregulates myocardial genes for oxidative phosphorylation and fatty acid metabolism in Gαq-mice. [PDF]

open access: yesJ Mol Cell Cardiol Plus
Chambers JM   +8 more
europepmc   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

open access: yesAdvanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su   +17 more
wiley   +1 more source

Comparative metabolomics analysis based on LC-MS method reveals regulatory difference in lipid metabolism and fatty acids metabolism between diploid and triploid rainbow trout (Oncorhynchus mykiss)

open access: yesAquaculture Reports
Diploid rainbow trout gonadal development occurs at the expense of stored energy and nutrients, lipid mobilization supplies energy required for this process.
Chenhui Li   +9 more
doaj  

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

open access: yesAdvanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu   +7 more
wiley   +1 more source

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

open access: yesNature, 2009
Erika L. Pearce   +7 more
semanticscholar   +1 more source

Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics

open access: yesAdvanced Science, EarlyView.
This study develops noninvasive clinical‐radiomic models using preoperative CT images to predict the malignant potential of pancreatic cystic lesions. It demonstrates the models' high accuracy across various datasets, with AUCs exceeding 0.92. Additionally, multi‐omics analyses uncover key biological mechanisms, including secretion function and lipid ...
Sihang Cheng   +14 more
wiley   +1 more source

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