Results 241 to 250 of about 1,111,197 (376)

HETEROGENEITY OF FOREARM METABOLISM WITH SPECIAL REFERENCE TO FREE FATTY ACIDS* [PDF]

, 1962
Marc Baltzan, Reubin Andres, Gordon Cader, Kenneth L. Zierler   +3 more
openalex   +1 more source

Analysis of readability of the top web searches for pediatric inborn errors of fatty acid metabolism. [PDF]

Mol Genet Metab Rep
Sawyer K, Miller W, Popp C, Strege C, Eide C, Tolar J.   +5 more
europepmc   +1 more source

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

Advanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang, Yunxing Huang, Yin Tong, Kenneth Tsz Chun Ng, Jiangwen Zhang   +4 more
wiley   +1 more source

Effect of Desoxypyridoxine-Induced Vitamin B6 Deficiency on Polyunsaturated Fatty Acid Metabolism in Human Beings

, 1963
John F. Mueller, James M. Iacono
openalex   +1 more source

Dysregulation of Fatty Acid Metabolism in Breast Cancer and Its Targeted Therapy. [PDF]

Breast Cancer (Dove Med Press)
Chang Y, Du R, Xia F, Xu X, Wang H, Chen X.   +5 more
europepmc   +1 more source

Mas Signaling Potentiates Neutrophil Extracellular Traps Formation Induced by Endothelial Cells Derived S1P in Mice with Acute Liver Failure

Advanced Science, EarlyView.
In mice challenged with lipopolysaccharide/D‐galactosamine (L/G), Mas signaling increased SHP2 in hepatic Col4a1+ endothelial cells, inhibiting farnesoid X receptor (FXR), potentially due to enterogenic deoxycholic acid. This inhibition activates sphingosine‐1‐phosphate‐induced Raf/MEK/ERK signaling in Cldn1+CD177+ neutrophils, causing neutrophil ...
Bo Yang, Shuai Chen, Xiaoqi Xia, Ziwen Tao, Chun Liu, Shanshan Li, Shuo Zhang, Jiali Huang, Lu Xia, Wenqiang Quan, Changqing Yang, Jing Li   +11 more
wiley   +1 more source

Camelina circRNA landscape: Implications for gene regulation and fatty acid metabolism. [PDF]

Plant Genome
Utley D, Edwards B, Budnick A, Grotewold E, Sederoff H.   +4 more
europepmc   +1 more source

hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation

Advanced Science, EarlyView.
This article addresses the absence of zonation features in current organoid models by co‐culturing human embryonic stem cell‐derived hepatocytes with liver sinusoidal endothelial cells exhibiting distinct zonal characteristics. It demonstrates that differential WNT2 signaling from endothelial cells modulates hepatocyte zonation and metabolic functions,
Yuying Zhang, Chenyan Huang, Lei Sun, Lyu Zhou, Yudi Niu, Kaini Liang, Bingjie Wu, Peng Zhao, Zhiqiang Liu, Xiaolin Zhou, Peng Zhang, Jianchen Wu, Jie Na, Yanan Du   +13 more
wiley   +1 more source

Fatty acid metabolism-derived prognostic model for lung adenocarcinoma: unraveling the link to survival and immune response. [PDF]

Front Immunol
Wu RZ, Sun QQ, Fu Y, Yu HN, Liu WY, Wu YH, Zhang H, Pan YL, Rui X.   +8 more
europepmc   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

Advanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang, Xudan Dou, Yongzhan Sun, Mengyao Wang, Jing Wang, Xinyi Cao, Haijie Xie, Linguo Xie, Weiping Tian, Jing Nie, Yupeng Chen, Chunyu Liu, Lirong Zhang   +12 more
wiley   +1 more source