Results 311 to 320 of about 1,111,197 (376)

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Advanced Science, EarlyView.
When the normal kidney is subjected to injurious stimuli, it can lead to persistent activation of ATG5. The activation of ATG5 promotes HSP90‐HIF‐1α interaction, resulting in stabilization of HIF‐1α and subsequent activation of glycolysis. Consequently, this process contributes to mitochondrial fission and inflammation, ultimately culminating in kidney
Yan Hu, Jinqing Li, Hui Chen, Yingfeng Shi, Xiaoyan Ma, Yi Wang, Xialin Li, Qin Zhong, Yishu Wang, Daofang Jiang, Shougang Zhuang, Na Liu   +11 more
wiley   +1 more source

Intermittent fasting, fatty acid metabolism reprogramming, and neuroimmuno microenvironment: mechanisms and application prospects. [PDF]

Front Nutr
Zhang A, Wang J, Zhao Y, He Y, Sun N.
europepmc   +1 more source

Multi-omics analysis and experimental verification reveal testicular fatty acid metabolism disorder in non-obstructive azoospermia. [PDF]

Zool Res
Li Z, Xiang YJ, Zou ZC, Feng YM, Wang H, Chen WQ, Ge X, Ma JZ, Jing J, Yao B.   +9 more
europepmc   +1 more source

The role of short-chain fatty acid metabolism in the pathogenesis, diagnosis and treatment of cancer. [PDF]

Front Oncol
Hou M, Yu QQ, Yang L, Zhao H, Jiang P, Qin L, Zhang Q.   +6 more
europepmc   +1 more source

Investigating the diagnostic and prognostic significance of genes related to fatty acid metabolism in hepatocellular carcinoma. [PDF]

BMC Gastroenterol
Zhao SS, Bai RR, Zhang BH, Sun XR, Huang N, Chen Y, Sun ZJ, Sun LM, Zhang Y, Cui ZQ.   +9 more
europepmc   +1 more source

Identification of Fatty Acid Metabolism-Related Subtypes in Gastric Cancer Aided by Machine Learning. [PDF]

Cancer Manag Res
Hou M, Chen J, Yang L, Qin L, Liu J, Zhao H, Guo Y, Yu QQ, Zhang Q.   +8 more
europepmc   +1 more source

CRSP8-driven fatty acid metabolism reprogramming enhances hepatocellular carcinoma progression by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling. [PDF]

J Exp Clin Cancer Res
Lin Y, Liang Z, Weng Z, Liu X, Zhang F, Chong Y.   +5 more
europepmc   +1 more source

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Fatty Acid Metabolism and Cancer

Advances in Experimental Medicine and Biology, 2021
Although normal cells depend on exogenous lipids to function and survive, excessive amount of body fat has been associated with increased risk for certain human cancers. Cancer cells can redirect metabolic pathways to meet energy demands through the regulation of fatty acid metabolism.
Yang D Chai, Zhenning Jin, Shen Hu
openaire   +3 more sources

Myocardial fatty acid metabolism in health and disease.

Physiological Reviews, 2010
There is a constant high demand for energy to sustain the continuous contractile activity of the heart, which is met primarily by the beta-oxidation of long-chain fatty acids.
G. Lopaschuk, J. Ussher, Clifford D. L. Folmes, J. Jaswal, W. Stanley   +4 more
semanticscholar   +1 more source

Fatty acid metabolism in phenylketonuria

European Journal of Pediatrics, 1996
Children treated for phenylketonuria (PKU) have a low intake of whole animal foods. Consequently, the dietary intake of long-chain polyunsaturated fatty acids (PUFA) is just a few milligrams per day, mostly represented by arachidonic acid (AA). In a consecutive series of studies, we assessed in treated PKU children their long-chain PUFA status, the AA ...
M. Giovannini, C. Agostoni, G. Biasucci, A. Rottoli, D. Luotti, S. Trojan, E. Riva   +6 more
openaire   +4 more sources