Results 91 to 100 of about 619,233 (330)

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

The protection of the unsaturated fatty acids of dried grass and sunflower seed against biohydrogenation by rumen micro-organisms : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Animal Science at Massey University [PDF]

, 1974
Ryegrass which had been dried and treated with HCHO was incubated with the rumen contents of a pasture-grazed cow. The protein in the grass was protected from degradation by the rumen microbes.
Smeaton, Duncan Colquhoun
core  

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Ruminal microbiome–host metabolome crosstalk in the synthesis of unsaturated fatty acids in buffalo milk

Journal of Dairy Science
: Interactions between rumen microorganisms and their metabolites contribute to milk yield and milk fat content in dairy cows. However, whether rumen microbes and host metabolism affect fatty acid synthesis in milk is unknown.
Ye Yu, Runqi Fu, Chunjia Jin, Huan Gao, Lin Han, Min Qi, Binlong Fu, Qian Li, Yuyan Wang, Yanfen Cheng, Jing Leng   +10 more
doaj   +1 more source

Quantitative Iron Measurements in the Basal Ganglia of NBIA Patients Using QSM: Insights From a Tertiary Center

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun, Alpay Özcan, Fuat Kaan Aras, Evrim Bozdemir, Sibel Uğur İşeri, Murat Gültekin, Nihan Hande Akçakaya, Orkhan Mammadov, Gülay Kır, Dilek İnce Günal, Neşe Tuncer, Fatma Betül Özdilek, Banu Özen Barut, Ercan Köse, Hülya Apaydın, Asuman Ali, Sultan Çağırıcı, Pınar Topaloğlu, Alp Dinçer, Zuhal Yapıcı   +19 more
wiley   +1 more source

Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling

Cell Reports, 2018
Summary: It is well understood that fatty acids can be synthesized, imported, and modified to meet requisite demands in cells. However, following the movement of fatty acids through the multiplicity of these metabolic steps has remained difficult.
Joseph P. Argus, Moses Q. Wilks, Quan D. Zhou, Wei Yuan Hsieh, Elvira Khialeeva, Xen Ping Hoi, Viet Bui, Shili Xu, Amy K. Yu, Eric S. Wang, Harvey R. Herschman, Kevin J. Williams, Steven J. Bensinger   +12 more
doaj   +1 more source

Experimental and modeling studies on the synthesis and properties of higher fatty esters of corn starch [PDF]

, 2009
This paper describes a systematic study on the synthesis of higher fatty esters of corn starch (starch laurate and starch stéarate) by using the corresponding vinyl esters.
Aburto, Aburto, Aburto, Aburto, Aburto, Ashby, Bastioli, Day, de Graaf, de Graaf, Dicke, Ehrenstein, Hernandez, Junistia, Laignel, Marsden, Montgomery, Mormann, Mullen, Mullen, Otey, Sagar, Stevens, Thiebaud, Wang   +24 more
core   +1 more source

Effects of Cyclodextrins on Fatty Acid Synthesis

Journal of Biological Chemistry, 1973
Abstract The stimulatory effects of the mycobacterial polysaccharides MMP (3-O-methylmannose containing polysaccharide) or MGLP (lipopolysaccharide containing 6-O-methylglucose and glucose) on the activity of the fatty acid synthetase from Mycobacterium phlei are mimicked by α-, β-, and γ-cyclodextrins in the order α g β g γ. Methylation to the hexakis
Konrad Bloch, Parke K. Flick, Raymond J. Bergeron, Yoshimasa Machida   +3 more
openaire   +2 more sources

Double‐Stranded DNA Reduces dsRNA Degradation in the Saliva and Significantly Enhanced RNAi‐Mediated Gene Silencing in Halyomorpha halys

Advanced Biology, EarlyView.
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni, Georg Petschenka, Aline Koch   +2 more
wiley   +1 more source

HMG-CoA reductase inhibitors perturb fatty acid metabolism and induce peroxisomes in keratinocytes.

Journal of Lipid Research, 1992
Topical lovastatin stimulates epidermal fatty acid synthesis in vivo; therefore, studies were undertaken to examine the effects of HMG-CoA reductase inhibitors on fatty acid metabolism in cultured keratinocytes.
ML Williams, GK Menon, KP Hanley
doaj   +1 more source