Results 171 to 180 of about 340,714 (313)
This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi+18 more
wiley +1 more source
Sex differences in the neuroinflammatory signaling pathway: effect of miRNAs on fatty acid synthesis in microglia. [PDF]
Zheng H+8 more
europepmc +1 more source
Synthesis of Fatty Acids in Animal Tissues
P.W. Holloway, Salih J. Wakil
openalex +1 more source
Advances in Microfluidic Cochlea‐On‐A‐Chip
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen+10 more
wiley +1 more source
Genomic and biochemical analyses of lipid biosynthesis in Cyanophora paradoxa: limited role of the chloroplast in fatty acid synthesis. [PDF]
Sato N, Ikemura E, Uemura M, Awai K.
europepmc +1 more source
Studies on lipogenesis in vivo: Comparison of cholesterol and fatty acid synthesis in rats and mice [PDF]
Gerrit Jansen+2 more
openalex +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao+14 more
wiley +1 more source
THE UTILIZATION OF ACETIC ACID FOR THE SYNTHESIS OF FATTY ACIDS
D. Rittenberg, Konrad Bloch
openaire +3 more sources
Cells transduce the rigidity of the environment into biochemical cues through mechanotransductive cascades that modulate cell behavior. Here, a novel role for the boron transporter NaBC1 is identified as a mechanotransducer involved in regulating cell behavior via specific crosstalk with fibronectin‐binding integrins.
Juan Gonzalez‐Valdivieso+9 more
wiley +1 more source