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Nitrated fatty acids: synthesis and measurement [PDF]
Free Radical Biology and Medicine, 2013 Nitrated fatty acids are the product of nitrogen dioxide reaction with unsaturated fatty acids. The discovery of peroxynitrite and peroxidase-induced nitration of biomolecules led to the initial reports of endogenous nitrated fatty acids. These species increase during ischemia/reperfusion, but concentrations are often at or near the limits of detection.
Woodcock, Steven R. +3 more
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Fatty Acid Synthesis by Elongases in Trypanosomes [PDF]
Cell, 2006 All eukaryotic and prokaryotic organisms are thought to synthesize fatty acids using a type I or type II synthase. In addition, eukaryotes extend pre-existing long chain fatty acids using microsomal elongases (ELOs). We have found that Trypanosoma brucei, a eukaryotic human parasite that causes sleeping sickness, uses three elongases instead of type I ...
Jennifer L. Stephens +3 more
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Synthesis of Benzophenone‐Containing Fatty Acids. [PDF]
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Yonghong Gan +2 more
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SGIV Induced and Exploited Cellular De Novo Fatty Acid Synthesis for Virus Entry and Replication
Viruses, 2022 Considerable attention has been paid to the roles of lipid metabolism in virus infection due to its regulatory effects on virus replication and host antiviral immune response. However, few literature has focused on whether lipid metabolism is involved in
Qi Zheng +6 more
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Microsomal Synthesis of Fatty Acid Amides [PDF]
Journal of Biological Chemistry, 1966 Abstract A microsomal system is described which catalyzes the formation of fatty acid amides of ethanolamine and of several pharmacologically active amines. Although the system has no dependance on external energy sources and has a high Km for the amine substrate, it has several characteristics which differ markedly from an amide hydrolytic system in ...
Nicholas R. Bachur, Sidney Udenfriend
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Frontiers in Bioengineering and Biotechnology, 2023 Sterols constitute vital structural and regulatory components of eukaryotic cells. In the oleaginous microorganism Schizochytrium sp. S31, the sterol biosynthetic pathway primarily produces cholesterol, stigmasterol, lanosterol, and cycloartenol. However,
Yali Bi +15 more
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The Long and Short of Fatty Acid Synthesis [PDF]
Cell, 2007 The multienzyme complex that synthesizes very long chain fatty acids is embedded in the membrane of the endoplasmic reticulum. In this issue, Denic and Weissman (2007) describe the reconstitution of this complex in liposomes and reveal how elongase proteins (Elops) determine the final length of the fatty acyl CoA chain.
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mBio, 2013 Enoyl-acyl carrier protein (enoyl-ACP) reductase catalyzes the last step of the elongation cycle in the synthesis of bacterial fatty acids. The Enterococcus faecalis genome contains two genes annotated as enoyl-ACP reductases, a FabI-type enoyl-ACP ...
Lei Zhu +6 more
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Mitochondrial fatty acid synthesis and respiration
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2010 Recent studies have revealed that mitochondria are able to synthesize fatty acids in a malonyl-CoA/acyl carrier protein (ACP)-dependent manner. This pathway resembles bacterial fatty acid synthesis (FAS) type II, which uses discrete, nuclearly encoded proteins. Experimental evidence, obtained mainly through using yeast as a model system, indicates that
Alexander J. Kastaniotis +10 more
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Biotechnology for Biofuels, 2018 Background The microbial production of fatty acids has received great attention in the last few years as feedstock for the production of renewable energy.
María Santos-Merino +2 more
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