Results 281 to 290 of about 340,714 (313)
Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
Advanced Science, EarlyView.The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan +16 more
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STK11 (LKB1) mutation suppresses ferroptosis in lung adenocarcinoma by facilitating monounsaturated fatty acid synthesis. [PDF]
Open Med (Wars)Zou Q, Tang B, Chen X, Zhang C, Huang Y.
europepmc +1 more source
Advanced Science, EarlyView.A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim +6 more
wiley +1 more source
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis. [PDF]
J Transl MedHao XL +14 more
europepmc +1 more source
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REGULATION OF FATTY ACID SYNTHESIS
Annual Review of Plant Physiology and Plant Molecular Biology, 1997▪ Abstract All plant cells produce fatty acids from acetyl-CoA by a common pathway localized in plastids. Although the biochemistry of this pathway is now well understood, much less is known about how plants control the very different amounts and types of lipids produced in different tissues.
Jan G. Jaworski, John B. Ohlrogge
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Mechanism of fatty acid synthesis
Life Sciences, 1977Abstract Significant advances have been made in the past few years in our understanding of the mechanism of synthesis of fatty acids, the structural organization of fatty acid synthetase complexes and the mechanism of regulation of activity of these enzyme systems.
Sarvagya S. Katiyar, John W. Porter
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Synthesis of the fatty acid of pramanicin [PDF]
Canadian Journal of Chemistry, 1997 The natural product tetradec-2-enoic acid-4,5-epoxide (2), which is also a component of the antibiotic pramanicin (1), was prepared in racemic form by a glycoluril-template directed approach. Two sequential additions of acetate units to decanoic acid are effected by intramolecular condensations on the template, mimicking the proposed biosynthetic ...
David Valentini +2 more
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1970
Abstract 1. 1. The fatty-acid synthesizing capacity of guinea-pig heart is confined to the mitochondria; no synthesis of fatty acid could be demonstrated in the microsomal or soluble fractions. 2. 2. ATP citrate lyase (EC 4.1.3.8) and acetyl-CoA carboxylase (EC 6.4.1.2), which in rat liver were localized in the non-particulate fraction of the
H.L. Elenbaas +2 more
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Abstract 1. 1. The fatty-acid synthesizing capacity of guinea-pig heart is confined to the mitochondria; no synthesis of fatty acid could be demonstrated in the microsomal or soluble fractions. 2. 2. ATP citrate lyase (EC 4.1.3.8) and acetyl-CoA carboxylase (EC 6.4.1.2), which in rat liver were localized in the non-particulate fraction of the
H.L. Elenbaas +2 more
openaire +3 more sources
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2017Mitochondria and fatty acids are tightly connected to a multiplicity of cellular processes that go far beyond mitochondrial fatty acid metabolism. In line with this view, there is hardly any common metabolic disorder that is not associated with disturbed mitochondrial lipid handling. Among other aspects of mitochondrial lipid metabolism, apparently all
Anne M. Mäkelä +10 more
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