Results 21 to 30 of about 1,679,926 (396)

Upregulation of Superenhancer‐Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma

Advanced Science, 2023
Superenhancers drive abnormal gene expression in tumors and promote malignancy. However, the relationship between superenhancer‐associated long noncoding RNA (lncRNA) and abnormal metabolism is unknown.
Jiang‐Yun Peng, Dian‐Kui Cai, Ren‐Li Zeng, Chao‐Yang Zhang, Guan‐Cheng Li, Si‐Fan Chen, Xiao‐Qing Yuan, Li Peng   +7 more
doaj   +1 more source

Elucidation of sterol biosynthesis pathway and its co-regulation with fatty acid biosynthesis in the oleaginous marine protist Schizochytrium sp.

Frontiers in Bioengineering and Biotechnology, 2023
Sterols constitute vital structural and regulatory components of eukaryotic cells. In the oleaginous microorganism Schizochytrium sp. S31, the sterol biosynthetic pathway primarily produces cholesterol, stigmasterol, lanosterol, and cycloartenol. However,
Yali Bi, Yali Bi, Yali Bi, Pengfei Guo, Pengfei Guo, Pengfei Guo, Liangsen Liu, Liangsen Liu, Liangsen Liu, Lei Chen, Lei Chen, Lei Chen, Weiwen Zhang, Weiwen Zhang, Weiwen Zhang, Weiwen Zhang   +15 more
doaj   +1 more source

Metabolic fates of isovaleric acid and isovalthine in rats [PDF]

, 1966
1. Isovaleric acid-1-C14, -4-C14, or C14-CaC03 with or without non-isotopic isovaleric acid was orally administered to rats and the incorporation of these isotopes into liver cholesterol, fatty acid, or urinary isovalthine was examined. 2.
Azumi, Tsukasa, Fujii, Yoshiro, Kodama, Hiroyuki, Shimomura, Takehira   +3 more
core   +1 more source

Composition and synthesis of fatty acids in atherosclerotic aortas of the pigeon

Journal of Lipid Research, 1968
The composition, synthesis, and esterification of fatty acids were studied in aortas of White Carneau and Show Racer pigeons after perfusion of the aortas with a medium containing acetate-1-14C.For both breeds of pigeons the principal change in aortic ...
Richard W. St. Clair, Hugh B. Lofland, Jr., Thomas B. Clarkson   +2 more
doaj   +1 more source

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

Journal of Clinical Investigation, 2023
Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear.
Jong-Seok Moon, Seonmin Lee, Mi-Ae Park, I. Siempos, M. Haslip, Patty J. Lee, Mijin Yun, C. Kim, J. Howrylak, S. Ryter, K. Nakahira, A. Choi   +11 more
semanticscholar   +1 more source

Preeclampsia is associated with compromized maternal synthesis of long chain polyunsaturated fatty acids leading to offspring deficiency [PDF]

, 2012
Obesity and excessive lipolysis are implicated in preeclampsia (PE). Intrauterine growth restriction is associated with low maternal body mass index and decreased lipolysis.
Brown, E.A., Freeman, D.J., Greer, I.A., Hodson, L., Huda, S.S., Jordan, F., Mackay, V.A., Martin, I., McKenna, L.A., Meyer, B.J., Stewart, F.M., Tham, K.   +11 more
core   +2 more sources

Nitrated fatty acids: synthesis and measurement [PDF]

Free Radical Biology and Medicine, 2013
Nitrated fatty acids are the product of nitrogen dioxide reaction with unsaturated fatty acids. The discovery of peroxynitrite and peroxidase-induced nitration of biomolecules led to the initial reports of endogenous nitrated fatty acids. These species increase during ischemia/reperfusion, but concentrations are often at or near the limits of detection.
Woodcock, Steven R., Bonacci, Gustavo Roberto, Gelhaus, Stacy L., Schopfer, Francisco J.   +3 more
openaire   +3 more sources

De novo fatty acid synthesis and elongation of fatty acids by subcellular fractions of lung

Journal of Lipid Research, 1971
Fatty acid synthesis by subcellular fractions of rabbit lung was studied by measuring the incorporation of either radioactive acetyl coenzyme A or malonyl coenzyme A into long-chain fatty acids.
HARVEY SCHILLER, KLAUS BENSCH
doaj   +1 more source

SGIV Induced and Exploited Cellular De Novo Fatty Acid Synthesis for Virus Entry and Replication

Viruses, 2022
Considerable attention has been paid to the roles of lipid metabolism in virus infection due to its regulatory effects on virus replication and host antiviral immune response. However, few literature has focused on whether lipid metabolism is involved in
Qi Zheng, Youhua Huang, Liqun Wang, Ya Zhang, Xixi Guo, Xiaohong Huang, Qiwei Qin   +6 more
doaj   +1 more source

Effect of supplementation with different fat sources on the mechanisms involved in reproductive performance in lactating dairy cattle [PDF]

, 2012
peer reviewedSupplementary fat positively influences reproductive performance in dairy cattle, although the mechanisms involved are not clearly defined. Our objective was to determine the effects of four different fat supplements on follicle development,
Butler, Stephen, Dewhurst, Richard J., Evans, A.C.O., Hennessy, Alan A., Hutchinson, Ian A., Lonergan, P., Waters, Sinead M.   +6 more
core   +1 more source